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Ligand · AZA

AZA · 8-azaxanthine

AZA, 8-azaxanthine (C4 H3 N5 O2, 153.1 g/mol), in the MolNFT structures on GenesisL1: bound in 52 records (31 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
AZA
Formula
C4 H3 N5 O2
Class
ligand
Structures
52
PDB entries
31

Binding sites

AZA in 52 structures; the first of them:

  • 5FRC · Structure of urate oxidase prepared by the 'soak-and-freeze' method under 42 bar of… · AZA A401 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 5UTJ · Crystal Structure of TGT in complex with 2,6-dioxy-8-azapurine, 2,6-dioxy-8-azapurine… · AZA A405 · binds ASP102, TYR106, GLN107, ASP156, ILE201, GLN203, GLY229, GLY230 and 3 more
  • 5Y2P · Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 89%… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 5YJA · Crystal structure of highly active BTUO mutant P287G without dehydration · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 5Z2B · Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86%… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 6I9X · urate oxidase under 35 bar of argon · AZA A1101 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 6I9Z · urate oxidase under 65 bar of argon · AZA A1101 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 6IA1 · urate oxidase under 120 bar of argon · AZA A1101 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 6IA9 · urate oxidase under 2000 bar (220 MPa) of argon · AZA aaa303 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254
  • 6IC1 · urate oxidase under 90 bar of krypton · AZA A1102 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 6RGM · urate oxidase under 130 bar of krypton · AZA A1107 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 7A0L · Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate… · AZA A401 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254
  • 7CMN · Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88%… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 7CMQ · Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88%… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 7CUF · Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 7CUG · Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride… · AZA A401 · binds PHE184, LEU195, ARG201, SER248, ILE249, GLN250, ASN276, GLN304 and 5 more
  • 7ELS · Crystal structure of xanthine riboswitch with 8-azaxanthine · AZA A109 · binds A6, G7, G10, C11, G35, A39, U40, U41
  • 7P0C · Urate oxidase with 8-azaxanthine under 210 mpa pressure · AZA A401 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 7P0D · Urate oxidase with 8-azaxanthine under 310 mpa pressure · AZA A401 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 7P0G · Urate oxidase with 8-azaxanthine under ambient pressure · AZA A401 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254, ILE288
  • 7PUF · urate oxidase azaxanthine complex under 600 bar (60 MPa) of argon · AZA A402 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254
  • 7PWN · URATE OXYDASE AZA-XANTHINE COMPLEX AT 1000 BARS (100 MPa) OF ARGON · AZA A1102 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254
  • 7Q09 · Urate oxidase aza-xanthine complex under 1500 bar of argon · AZA A303 · binds PHE159, LEU170, ARG176, SER226, VAL227, GLN228, ASN254

Residues it binds most

GLN 92, LEU 100, PHE 100, ARG 90, SER 90, VAL 87, ASN 78, TYR 58, ILE 58, ASP 53 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • OXY · Oxygen molecule
  • SO4 · Sulfate ion
  • ACE · Acetyl group
  • AR · Argon
  • EDO · 1,2-ethanediol
  • MXE · 2-methoxyethanol
  • ACT · Acetate ion
  • K · Potassium ion
  • CL · Chloride ion
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • KR · Krypton

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