UniProt Q42290
Probable mitochondrial-processing peptidase subunit beta, mitochondrial (Q42290)
Probable mitochondrial-processing peptidase subunit beta, mitochondrial (UniProt Q42290), EC 3.4.24.64: 4 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 30 pockets. Binding sites, druggability and…
- UniProt
- Q42290
- Protein
- Probable mitochondrial-processing peptidase subunit beta, mitochondrial
- EC
- 3.4.24.64
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 30 · 5 records with a druggable one
Structures
5 records of Q42290 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8BEP | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CIII MPP domain) | electron microscopy | B, L | ZN | 15 (best 0.83) |
| 8BPX | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition) | electron microscopy | AB, BB | ZN, PTY, PC7, PGT, CDL | 3 (best 0.83) |
| 8BQ5 | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1… | electron microscopy | AB, BB | ZN | 3 (best 0.83) |
| 8BQ6 | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2… | electron microscopy | AB, BB | ZN | 3 (best 0.84) |
| Q42290 | AlphaFold monomer V2.0 prediction for probable mitochondrial- processing peptidase subunit beta… | predicted | A | — | 6 (best 0.68) |
Ligands
- ZN · Zinc ion · in 4 records
- CDL · Cardiolipin · in 1 record
- PC7 · (7S)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[(palmitoyloxy) methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide · in 1 record
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 1 record
- PTY · Phosphatidylethanolamine · in 1 record
Experiment against prediction
- 8BQ5 chain BB against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BEP chain B against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BPX chain AB against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BPX chain BB against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BEP chain L against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BQ5 chain AB against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BQ6 chain AB against the predicted model Q42290: TM-score 0.99, RMSD 0.75 Å
- 8BQ6 chain BB against the predicted model Q42290: TM-score 0.99, RMSD 0.76 Å
Elsewhere
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