UniProt Q3UIU2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (Q3UIU2)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (UniProt Q3UIU2): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q3UIU2
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 19 · 6 records with a druggable one
Structures
15 records of Q3UIU2 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | i | CDL, 3PE | 3 (best 0.88) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | i | CDL, 3PE | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | i | — | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | i | 3PE, CDL | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | i | CDL, 3PE | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | i | CDL, 3PE | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | i | CDL, 3PE | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | i | — | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | i | CDL, 3PE | — |
| 8IAQ | Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… | electron microscopy | i | CDL, 3PE | 6 (best 0.87) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | i | CDL, 3PE | 2 (best 0.86) |
| 8IC4 | Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold… | electron microscopy | i | CDL, 3PE | 4 (best 0.87) |
| 8PW6 | C respirasome from murine liver | electron microscopy | i1 | CDL, 3PE | 1 (best 0.88) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | i | CDL, 3PE | 3 (best 0.88) |
| Q3UIU2 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6… | predicted | A | — | — |
Ligands
Experiment against prediction
- 7AK5 chain i against the predicted model Q3UIU2: TM-score 0.73, RMSD 2.52 Å
- 7AK5 chain i against the predicted model Q3UIU2: TM-score 0.73, RMSD 2.52 Å
- 6G2J chain i against the predicted model Q3UIU2: TM-score 0.72, RMSD 3.08 Å
- 6G2J chain i against the predicted model Q3UIU2: TM-score 0.72, RMSD 3.08 Å
- 7AK6 chain i against the predicted model Q3UIU2: TM-score 0.72, RMSD 2.58 Å
- 6ZTQ chain i against the predicted model Q3UIU2: TM-score 0.72, RMSD 2.61 Å
- 6ZR2 chain i against the predicted model Q3UIU2: TM-score 0.71, RMSD 2.67 Å
- 6G72 chain i against the predicted model Q3UIU2: TM-score 0.71, RMSD 3.01 Å
- 7B93 chain i against the predicted model Q3UIU2: TM-score 0.71, RMSD 2.63 Å
- 8PW6 chain i1 against the predicted model Q3UIU2: TM-score 0.71, RMSD 3.16 Å
Elsewhere
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