UniProt Q3U0P1
Partner and localizer of BRCA2 (Q3U0P1)
Partner and localizer of BRCA2 (UniProt Q3U0P1): 4 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3U0P1
- Protein
- Partner and localizer of BRCA2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
5 records of Q3U0P1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6E4H | Solution NMR Structure of the Colied-coil PALB2 Homodimer | solution nmr | A, B | — | — |
| 6E4H | Solution NMR structure of the colied-coil PALB2 homodimer | solution nmr | A, B | — | — |
| 7K3S | Solution NMR Structure of the Coiled-coil BRCA1-PALB2 Heterodimer | solution nmr | B | — | 2 (best 0.32) |
| 7K3S | Solution NMR structure of the coiled-coil BRCA1-PALB2 heterodimer | solution nmr | B | — | — |
| Q3U0P1 | AlphaFold monomer V2.0 prediction for partner and localizer of BRCA2 (Q3U0P1) | predicted | A | — | 6 (best 0.79) |
Experiment against prediction
- 6E4H chain A against the predicted model Q3U0P1: TM-score 0.62, RMSD 2.96 Å
- 6E4H chain A against the predicted model Q3U0P1: TM-score 0.62, RMSD 2.96 Å
- 7K3S chain B against the predicted model Q3U0P1: TM-score 0.49, RMSD 2.53 Å
- 7K3S chain B against the predicted model Q3U0P1: TM-score 0.49, RMSD 2.53 Å
Elsewhere
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