UniProt Q3TDN0
Protein dispatched homolog 1 (Q3TDN0)
Protein dispatched homolog 1 (UniProt Q3TDN0): 8 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 59 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3TDN0
- Protein
- Protein dispatched homolog 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 59 · 4 records with a druggable one
Structures
9 records of Q3TDN0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7RPH | Cryo-EM structure of murine Dispatched 'R' conformation | electron microscopy | A | NA, Y01, AV0, NAG | 12 (best 0.65) |
| 7RPH | Cryo-EM structure of murine dispatched 'R' conformation | electron microscopy | A | NA, Y01, AV0, NAG | — |
| 7RPI | Cryo-EM structure of murine Dispatched 'T' conformation | electron microscopy | A | Y01, AV0, NAG, NA | 15 (best 0.65) |
| 7RPI | Cryo-EM structure of murine dispatched 'T' conformation | electron microscopy | A | Y01, AV0, NAG, NA | — |
| 7RPJ | Cryo-EM structure of murine Dispatched NNN mutant | electron microscopy | A | NAG, Y01 | 13 (best 0.65) |
| 7RPJ | Cryo-EM structure of murine dispatched nnn mutant | electron microscopy | A | NAG, Y01 | — |
| 7RPK | Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | electron microscopy | A | Y01, AV0, NA, 6OE, NAG, SO4 | 19 (best 0.73) |
| 7RPK | Cryo-EM structure of murine dispatched in complex with sonic hedgehog | electron microscopy | A | Y01, AV0, NA, 6OE, NAG, SO4 | — |
| Q3TDN0 | AlphaFold monomer V2.0 prediction for protein dispatched homolog 1 (Q3TDN0) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- Y01 · Cholesterol hemisuccinate · in 8 records
- AV0 · 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside · in 6 records
- NA · Sodium ion · in 6 records
- 6OE · (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate · in 2 records
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 7RPI chain A against the predicted model Q3TDN0: TM-score 0.97, RMSD 1.62 Å
- 7RPI chain A against the predicted model Q3TDN0: TM-score 0.97, RMSD 1.62 Å
- 7RPK chain A against the predicted model Q3TDN0: TM-score 0.96, RMSD 2.02 Å
- 7RPK chain A against the predicted model Q3TDN0: TM-score 0.96, RMSD 2.02 Å
- 7RPH chain A against the predicted model Q3TDN0: TM-score 0.96, RMSD 2.12 Å
- 7RPH chain A against the predicted model Q3TDN0: TM-score 0.96, RMSD 2.12 Å
- 7RPJ chain A against the predicted model Q3TDN0: TM-score 0.95, RMSD 2.21 Å
- 7RPJ chain A against the predicted model Q3TDN0: TM-score 0.95, RMSD 2.21 Å
Elsewhere
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