UniProt Q39243
NADPH dependent thioredoxin reductase (Q39243)
NADPH dependent thioredoxin reductase (UniProt Q39243), EC 1.6.4.5: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q39243
- Protein
- NADPH dependent thioredoxin reductase
- EC
- 1.6.4.5
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
3 records of Q39243 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1VDC | Structure of NADPH dependent thioredoxin reductase | x-ray diffraction | A | SO4, FAD | 4 (best 0.81) |
| 1VDC | Structure of NADPH dependent thioredoxin reductase | x-ray diffraction | A | — | — |
| Q39243 | AlphaFold monomer V2.0 prediction for thioredoxin reductase 1, mitochondrial (Q39243) | predicted | A | — | 3 (best 0.79) |
Ligands
Experiment against prediction
- 1VDC chain A against the predicted model Q39243: TM-score 0.99, RMSD 0.62 Å
- 1VDC chain A against the predicted model Q39243: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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