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UniProt Q39128

Potassium channel KAT1 (Q39128)

Potassium channel KAT1 (UniProt Q39128): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 41 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q39128
Protein
Potassium channel KAT1
Experimental structures
12
Predicted models
1
Ligands
4
Pockets
41 · 2 records with a druggable one

Structures

13 records of Q39128 in the MolNFT archive: 12 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5NWI14-3-3c in complex with CPPx-ray diffractionP——
5NWI14-3-3C in complex with cppx-ray diffractionP——
5NWJ14-3-3c in complex with CPP7x-ray diffractionP—1 (best 0.49)
5NWJ14-3-3C in complex with CPP7x-ray diffractionP——
5NWK14-3-3c in complex with CPP and fusicoccinx-ray diffractionP, Q, R, S, T, U, V, WFSC—
5NWK14-3-3C in complex with cpp and fusicoccinx-ray diffractionP, Q, R, S, T, U, V, WFSC—
6V1XCryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramerelectron microscopyA, B, C, DQNP, QNJ20 (best 0.82)
6V1XCryo-EM structure of the hyperpolarization-activated potassium channel KAT1: tetramerelectron microscopyA, B, C, DQNP, QNJ—
6V1YCryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Octamerelectron microscopyA, B, C, D, M, N, O, PQNP, QNJ20 (best 0.82)
6V1YCryo-EM structure of the hyperpolarization-activated potassium channel KAT1: octamerelectron microscopyA, B, C, D, M, N, O, PQNP, QNJ—
7CALCryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1…electron microscopyA, B, C, D3PE—
7CALCryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1…electron microscopyA, B, C, D3PE—
Q39128AlphaFold monomer V2.0 prediction for potassium channel KAT1 (Q39128)predictedA——

Ligands

  • QNJ · (3beta,5beta,14beta,17alpha)-cholestan-3-ol · in 4 records
  • QNP · (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate · in 4 records
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 2 records
  • FSC · Fusicoccin · in 2 records

Experiment against prediction

Elsewhere

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