UniProt Q38CA1
Hypoxanthine-guanine phosphoribosyltransferase (Q38CA1)
Hypoxanthine-guanine phosphoribosyltransferase (UniProt Q38CA1), EC 2.4.2.8: 12 experimental structures on GenesisL1, 7 ligands bound, 95 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q38CA1
- Protein
- Hypoxanthine-guanine phosphoribosyltransferase
- EC
- 2.4.2.8
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 95 · 6 records with a druggable one
Structures
12 records of Q38CA1 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AQO | Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with… | x-ray diffraction | A, B, C, D, E, F | 45T, MG | 16 (best 0.77) |
| 6AQO | Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with… | x-ray diffraction | A, B, C, D, E, F | 45T, MG | — |
| 6AR9 | Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with… | x-ray diffraction | A, B, C, D, E, F | 3L4, MG | 16 (best 0.77) |
| 6AR9 | Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with… | x-ray diffraction | A, B, C, D, E, F | 3L4, MG | — |
| 6MXB | Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D, E, F | XMP, MG | 18 (best 0.77) |
| 6MXB | Crystal structure of trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D, E, F | XMP, MG | — |
| 6MXC | Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D, E, F | 5GP, MG | 16 (best 0.77) |
| 6MXC | Crystal structure of trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D, E, F | 5GP, MG | — |
| 6MXD | Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D | IMP, MG | 9 (best 0.57) |
| 6MXD | Crystal structure of trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in… | x-ray diffraction | A, B, C, D | IMP, MG | — |
| 7SCR | Crystal structure of trypanosome brucei hypoxanthine-guanine-xanthine phosphoribzosyltransferase in… | x-ray diffraction | A, C, B, D, E, F | 8QI | 20 (best 0.77) |
| 7SCR | Crystal structure of trypanosome brucei hypoxanthine-guanine-xanthine phosphoribzosyltransferase in… | x-ray diffraction | A, C, B, D, E, F | 8QI | — |
Ligands
- MG · Magnesium ion · in 10 records
- 3L4 · [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl) ethyl][(e)-2-phosphonoethenyl]amino}ethoxy) methyl]phosphonic acid · in 2 records
- 45T · {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl) propane-1,2-diyl]bis(oxyethane-2,1-diyl) }bis(phosphonic acid) · in 2 records
- 5GP · Guanosine-5'-monophosphate · in 2 records
- 8QI · ({(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2S)-2-hydroxy-2-phosphonoethoxy]propoxy}methyl) phosphonic acid · in 2 records
- IMP · Inosinic acid · in 2 records
- XMP · Xanthosine-5'-monophosphate · in 2 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.