UniProt Q32KD2
Histone-lysine N-methyltransferase eggless (Q32KD2)
Histone-lysine N-methyltransferase eggless (UniProt Q32KD2), EC 2.1.1.355: 4 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q32KD2
- Protein
- Histone-lysine N-methyltransferase eggless
- EC
- 2.1.1.355
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 23 · 1 record with a druggable one
Structures
5 records of Q32KD2 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UVE | Drosophila melanogaster setdb1-tuor domain with peptide H3K9me2K14ac | x-ray diffraction | A | — | 1 (best 0.49) |
| 7UVE | Drosophila melanogaster SETDB1-tuor domain with peptide H3K9ME2K14AC | x-ray diffraction | A | — | — |
| 7UW8 | Drosophila melanogaster setdb1-tuor domain | x-ray diffraction | A | — | 2 (best 0.49) |
| 7UW8 | Drosophila melanogaster SETDB1-tuor domain | x-ray diffraction | A | — | — |
| Q32KD2 | AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase eggless (Q32KD2) | predicted | A | — | 20 (best 0.75) |
Experiment against prediction
- 7UW8 chain A against the predicted model Q32KD2: TM-score 0.97, RMSD 1.12 Å
- 7UW8 chain A against the predicted model Q32KD2: TM-score 0.97, RMSD 1.12 Å
- 7UVE chain A against the predicted model Q32KD2: TM-score 0.96, RMSD 1.33 Å
- 7UVE chain A against the predicted model Q32KD2: TM-score 0.96, RMSD 1.33 Å
Elsewhere
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