UniProt Q2N0S7
Envelope Glycoprotein gp41 (Q2N0S7)
Envelope Glycoprotein gp41 (UniProt Q2N0S7): 40 experimental structures on GenesisL1, 5 ligands bound, 218 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q2N0S7
- Protein
- Envelope Glycoprotein gp41
- Experimental structures
- 40
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 218 · 25 records with a druggable one
Structures
40 records of Q2N0S7 in the MolNFT archive: 40 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CDE | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1… | electron microscopy | D, d, 1 | NAG | 8 (best 0.83) |
| 6CDI | Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1… | electron microscopy | c, A, D | NAG, BMA | — |
| 6CH7 | XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex… | x-ray diffraction | B | NAG, FUC | 5 (best 0.61) |
| 6CH7 | Xfel crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV- 1 envelope trimer in complex… | x-ray diffraction | B | NAG, FUC | — |
| 6CH8 | Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with… | x-ray diffraction | B | NAG | 3 (best 0.67) |
| 6CH8 | Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 envelope trimer in complex with… | x-ray diffraction | B | NAG | — |
| 6CHB | Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with… | x-ray diffraction | B, A, C | — | 6 (best 0.84) |
| 6CHB | Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 envelope trimer in complex with… | x-ray diffraction | B, A, C | — | — |
| 6CM3 | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | electron microscopy | A, B, C | NAG | 9 (best 0.85) |
| 6CM3 | BG505 sosip in complex with SCD4, 17B, 8ANC195 | electron microscopy | A, B, C | NAG | — |
| 6CRQ | Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab | electron microscopy | C, G, H | NAG | 5 (best 0.84) |
| 6CRQ | Glutaraldehyde-treated BG505 SOSIP.664 env in complex with PGV04 Fab | electron microscopy | C, G, H | NAG | — |
| 6CUE | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1… | electron microscopy | 1, D, d | — | 12 (best 0.82) |
| 6CUF | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1… | electron microscopy | D, A, c | NAG | 9 (best 0.84) |
| 6DE7 | Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env… | x-ray diffraction | B | NAG | 6 (best 0.57) |
| 6DE7 | Crystal structure at 4.3 a resolution of glycosylated HIV-1 clade a BG505 SOSIP.664 prefusion env… | x-ray diffraction | B | NAG | — |
| 6DID | HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 | electron microscopy | B, I, J | NAG | 6 (best 0.82) |
| 6DID | HIV env BG505 sosip with polyclonal fabs from immunized rabbit #3417 post-BOOST#1 | electron microscopy | B, I, J | NAG | — |
| 6MAR | HIV-1 Envelope Glycoprotein Clone BG505 delCT N332T in complex with broadly neutralizing antibody… | electron microscopy | B, D, F | NAG, GAL, FUC | — |
| 6MAR | HIV-1 envelope glycoprotein clone BG505 delct N332T in complex with broadly neutralizing antibody… | electron microscopy | B, D, F | NAG, GAL, FUC | — |
| 6MN7 | Cryo-EM structure of BG505.SOSIP.664 in complex with BF520.1 antigen binding fragment | electron microscopy | B, E, F | NAG | 5 (best 0.89) |
| 6MN7 | Cryo-EM structure of BG505.SOSIP.664 in complex with BF520.1 antigen binding fragment | electron microscopy | B, E, F | NAG | — |
| 6MPG | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01… | electron microscopy | U, A, D | NAG | — |
| 6MPH | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01… | electron microscopy | 6, D, E | NAG | 10 (best 0.83) |
| 6N1W | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1… | electron microscopy | A, D, d | — | 11 (best 0.81) |
| 6UM5 | Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT env | electron microscopy | B, F, J | — | 10 (best 0.79) |
| 6UM6 | Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env | electron microscopy | B, F, J | — | 7 (best 0.83) |
| 6UM6 | Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT env | electron microscopy | B, F, J | — | 7 (best 0.83) |
| 6UM7 | Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848… | electron microscopy | H, D, 1 | NAG | 7 (best 0.79) |
| 6UM7 | Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.MU1 in complex with CH848… | electron microscopy | H, D, 1 | NAG | 7 (best 0.79) |
| 6V8Z | VRC03 and 10-1074 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure | electron microscopy | B, H, N | NAG | 10 (best 0.84) |
| 6V8Z | VRC03 and 10-1074 bound BG505 F14 HIV-1 sosip envelope trimer structure | electron microscopy | B, H, N | NAG | — |
| 7LL1 | Cryo-EM structure of BG505 DS-SOSIP in complex with glycan276-dependent broadly neutralizing… | electron microscopy | B, D, I | NAG, BMA | 13 (best 0.83) |
| 7LL1 | Cryo-EM structure of BG505 ds-sosip in complex with GLYCAN276- dependent broadly neutralizing… | electron microscopy | B, D, I | NAG, BMA | — |
| 7LL2 | Cryo-EM structure of BG505 DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing… | electron microscopy | B, D, F | NAG | 9 (best 0.80) |
| 7LL2 | Cryo-EM structure of BG505 ds-sosip in complex with GLYCAN276- dependent broadly neutralizing… | electron microscopy | B, D, F | NAG | — |
| 7N65 | Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664 | electron microscopy | B, F, J | NAG, BMA | 12 (best 0.81) |
| 8FR6 | Antibody vFP53.02 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | electron microscopy | A, B, F | NAG | 14 (best 0.83) |
| 8G4M | Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | electron microscopy | A, B, F | NAG, MAN | 14 (best 0.82) |
| 8G4T | Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | electron microscopy | A, B, F | NAG | 13 (best 0.80) |
Ligands
Elsewhere
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