UniProt Q2IU02
Cytochrome P450 (Q2IU02)
Cytochrome P450 (UniProt Q2IU02), EC 1.-.-.-, 1.14.-.-: 73 experimental structures on GenesisL1, 39 ligands bound, 42 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q2IU02
- Protein
- Cytochrome P450
- EC
- 1.-.-.-, 1.14.-.-
- Experimental structures
- 73
- Predicted models
- 0
- Ligands
- 39
- Pockets
- 42 · 19 records with a druggable one
Structures
73 records of Q2IU02 in the MolNFT archive: 73 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DNZ | The crystal structures of CYP199A4 | x-ray diffraction | A, B, C, D | — | — |
| 4DNZ | The crystal structures of CYP199A4 | x-ray diffraction | A, B, C, D | — | — |
| 4DO1 | The crystal structures of 4-methoxybenzoate bound CYP199A4 | x-ray diffraction | A, B, C, D | — | — |
| 4DO1 | The crystal structures of 4-methoxybenzoate bound CYP199A4 | x-ray diffraction | A, B, C, D | — | — |
| 4EGM | The X-ray crystal structure of CYP199A4 in complex with 4-ethylbenzoic acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGM | The X-ray crystal structure of CYP199A4 in complex with 4-ethylbenzoic acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGN | The X-ray crystal structure of CYP199A4 in complex with veratric acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGN | The X-ray crystal structure of CYP199A4 in complex with veratric acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGO | The X-ray crystal structure of CYP199A4 in complex with indole-6-carboxylic acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGO | The X-ray crystal structure of CYP199A4 in complex with indole-6- carboxylic acid | x-ray diffraction | A, B, C, D | — | — |
| 4EGP | The X-ray crystal structure of CYP199A4 in complex with 2-naphthoic acid | x-ray diffraction | A, B | — | — |
| 4EGP | The X-ray crystal structure of CYP199A4 in complex with 2-naphthoic acid | x-ray diffraction | A, B | — | — |
| 5KDB | The crystal structure of 4-isopropylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 4IA, CL | — |
| 5KDB | The crystal structure of 4-isopropylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 4IA, CL | — |
| 5KDY | The crystal structure of the D251N mutant of CYP199A4 in complex with 4-methoxybenzoate | x-ray diffraction | A | HEM, ANN, CL | — |
| 5KDZ | The crystal structure of the T252A mutant of CYP199A4 in complex with 4-methoxybenzoate | x-ray diffraction | A | ANN, HEM, CL | 2 (best 0.85) |
| 5KDZ | The crystal structure of the T252A mutant of CYP199A4 in complex with 4-methoxybenzoate | x-ray diffraction | A | ANN, HEM, CL | — |
| 5KT1 | The crystal structure of 4-methylthiobenzoate-bound CYP199A4 | x-ray diffraction | A | 4MI, HEM, CL | 2 (best 0.86) |
| 5KT1 | The crystal structure of 4-methylthiobenzoate-bound CYP199A4 | x-ray diffraction | A | 4MI, HEM, CL | — |
| 5U6T | The crystal structure of 4-ethoxybenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 81J, CL | — |
| 5U6U | The crystal structure of 4-ethylthiobenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 81M, CL | — |
| 5U6U | The crystal structure of 4-ethylthiobenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 81M, CL | — |
| 5U6W | The crystal structure of 4-methylaminobenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 81P, CL | 2 (best 0.85) |
| 5U6W | The crystal structure of 4-methylaminobenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 81P, CL | — |
| 5UVB | The crystal structure of 4-cyclopropylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, CL, 8QM | — |
| 5YQA | The crystal structure of CYP199A4 binding with 4-n-Propyl benzoic acid | x-ray diffraction | A | HEM, 8ZU, CL | — |
| 5YQA | The crystal structure of CYP199A4 binding with 4-N-propyl benzoic acid | x-ray diffraction | A | HEM, 8ZU, CL | — |
| 5YQH | The crystal structure of CYP199A4 binding with 4-N-propyl benzoic acid | x-ray diffraction | A, B, C, D | HEM, 8ZX, CL, SO4 | — |
| 6C2D | The crystal structure of 4-cyclohexylbenzoate-bound CYP199A4 | x-ray diffraction | A | CL, HEM, EH1 | — |
| 6C2D | The crystal structure of 4-cyclohexylbenzoate-bound CYP199A4 | x-ray diffraction | A | CL, HEM, EH1 | — |
| 6C3H | The crystal structure of 4-n-heptylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, EJV, CL | — |
| 6C3H | The crystal structure of 4-N-heptylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, EJV, CL | — |
| 6C3J | The crystal structure of 4-(thiophen-3-yl)benzoate-bound CYP199A4 | x-ray diffraction | A | EJD, HEM, CL | 3 (best 0.85) |
| 6C3J | The crystal structure of 4-(thiophen-3-YL)BENZOATE-bound CYP199A4 | x-ray diffraction | A | EJD, HEM, CL | — |
| 6OOW | The crystal structure of 4-ethylbenzoate bound to T252A mutant of CYP199A4 | x-ray diffraction | A | CL, HEM, EGM | — |
| 6OOX | The crystal structure of 4-isopropylbenzoate bound to T252A mutant of CYP199A4 | x-ray diffraction | A | HEM, 4IA, CL | — |
| 6PQ6 | The crystal structure of 3-methoxybenzoate-bound CYP199A4 | x-ray diffraction | A | OVM, HEM, CL | — |
| 6PQD | The crystal structure of 3-methylthiobenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, OVP, CL | — |
| 6PQS | The crystal structure of 4-methylbenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, 4MA, CL | — |
| 6PQW | The crystal structure of 3-methylbenzoate-bound CYP199A4 | x-ray diffraction | A | OVV, HEM, CL | 3 (best 0.85) |
| 6PRR | The crystal structure of 3-methylaminobenzoate-bound CYP199A4 | x-ray diffraction | A | OW4, HEM, CL | — |
| 6PRS | The crystal structure of 3-ethoxybenzoate-bound CYP199A4 | x-ray diffraction | A | HEM, OW7, CL | — |
| 6U30 | The crystal structure of 4-pyridin-3-ylbenzoate-bound CYP199A4 | x-ray diffraction | A | PQM, HEM, CL | 2 (best 0.85) |
| 6U30 | The crystal structure of 4-pyridin-3-ylbenzoate-bound CYP199A4 | x-ray diffraction | A | PQM, HEM, CL | — |
| 6U31 | The crystal structure of 4-(1H-imidazol-1-YL)BENZOATE-bound CYP199A4 | x-ray diffraction | A | HEM, PQP, CL | — |
| 6U3K | The crystal structure of 4-(pyridin-2-yl)benzoate-bound CYP199A4 | x-ray diffraction | A | HEM, CL, PQS | 2 (best 0.85) |
| 6U3K | The crystal structure of 4-(pyridin-2-YL)BENZOATE-bound CYP199A4 | x-ray diffraction | A | HEM, CL, PQS | — |
| 6UNN | The crystal structure of 4-methoxycinnamic acid-bound CYP199A4 | x-ray diffraction | A | HEM, K3Z, CL | — |
| 6VJX | The crystal structure of 4-isobutylbenzoic acid-bound CYP199A4 | x-ray diffraction | A | HEM, QZP, CL | — |
| 6WZP | The crystal structure of 4-vinylbenzoate-bound T252A mutant CYP199A4 | x-ray diffraction | A | CL, HEM, MW7 | 2 (best 0.85) |
| 6WZP | The crystal structure of 4-vinylbenzoate-bound T252A mutant CYP199A4 | x-ray diffraction | A | CL, HEM, MW7 | — |
| 7JW5 | Crystal structure of wt-CYP199A4 in complex with 4-phenylbenzoic acid | x-ray diffraction | A | Z7Z, HEM, CL | — |
| 7JXB | The crystal structure of 4-(3'-METHOXYPHENYL)BENZOIC acid-bound CYP199A4 | x-ray diffraction | A | VLG, HEM, CL | — |
| 7KCS | The crystal structure of 4-vinylbenzoate-bound wild-type CYP199A4 | x-ray diffraction | A | CL, HEM, MW7 | 2 (best 0.85) |
| 7KCS | The crystal structure of 4-vinylbenzoate-bound wild-type CYP199A4 | x-ray diffraction | A | CL, HEM, MW7 | — |
| 7N14 | Crystal structure of 4-(1H-1,2,4-triazol-1-YL)BENZOIC acid-bound CYP199A4 | x-ray diffraction | A | ZRS, HEM, CL | — |
| 7N60 | The crystal structure of 4-methoxybenzoate-bound CYP199A S244D mutant | x-ray diffraction | A | HEM, ANN, MG, CL | 2 (best 0.85) |
| 7N60 | The crystal structure of 4-methoxybenzoate-bound CYP199A S244D mutant | x-ray diffraction | A | HEM, ANN, CL | — |
| 7R8S | The crystal structure of CYP199A4 bound to 4-n-propylbenzoic acid | x-ray diffraction | A | HEM, 8ZU, CL | — |
| 7R8S | The crystal structure of CYP199A4 bound to 4-N-propylbenzoic acid | x-ray diffraction | A | HEM, 8ZU, CL | — |
13 records more on the page itself.
Ligands
- HEM · Protoporphyrin IX containing Fe · in 61 records
- CL · Chloride ion · in 59 records
- ANN · 4-methoxybenzoic acid · in 6 records
- 8ZU · 4-propylbenzoic acid · in 5 records
- MW7 · 4-ethenylbenzoic acid · in 4 records
- 4IA · 4-propan-2-ylbenzoic acid · in 3 records
- EJD · 4-(thiophen-3-yl)benzoic acid · in 3 records
- PQS · 4-(pyridin-2-yl)benzoic acid · in 3 records
- 4MA · 4-methylbenzoic acid · in 2 records
- 4MI · 4-methylsulfanylbenzoic acid · in 2 records
- 81M · 4-(ethylsulfanyl)benzoic acid · in 2 records
- 81P · 4-(methylamino)benzoic acid · in 2 records
- EGM · 4-ethylbenzoic acid · in 2 records
- EH1 · 4-cyclohexylbenzoic acid · in 2 records
- EJV · 4-heptylbenzoic acid · in 2 records
- MG · Magnesium ion · in 2 records
- PQM · 4-(pyridin-3-yl)benzoic acid · in 2 records
- 174 · 4-chloro-benzoic acid · in 1 record
- 81J · 4-ethoxybenzoic acid · in 1 record
- 8QM · 4-cyclopropylbenzoic acid · in 1 record
- 8ZX · 4-methoxybenzamide · in 1 record
- JO4 · 4-phenoxybenzoic acid · in 1 record
- K3Z · (E)-3-(4-methoxyphenyl)acrylic acid · in 1 record
- KQR · 4-(thiophen-2-yl)benzoic acid · in 1 record
- KZ6 · 4-iodobenzoic acid · in 1 record
- L3C · 4-(chloromethyl)benzoic acid · in 1 record
- L6X · 4-methoxy-3-oxidanyl-benzoic acid · in 1 record
- OVM · 3-methoxybenzoic acid · in 1 record
- OVP · 3-(methylsulfanyl)benzoic acid · in 1 record
- OVV · 3-methylbenzoic acid · in 1 record
Elsewhere
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