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Ligand · FIV

FIV · naphthalene-2-carboxylic acid

FIV, naphthalene-2-carboxylic acid (C11 H8 O2, 172.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
FIV
Formula
C11 H8 O2
Class
ligand
Structures
3
PDB entries
3

Binding sites

FIV in 3 structures; the first of them:

  • 6TIB · Structure of A. niger Fdc I327S variant in complex with 2 naphthoic acid · FIV AAA605 · binds ARG173, LEU185, ILE187, GLN190, PHE280, GLU282, MET283, CYS316 and 6 more
  • 6TIL · Structure of A. niger Fdc WT in complex with FMN and 2 naphthoic acid · FIV AAA605 · binds ARG173, LEU185, ILE187, GLN190, PHE280, GLU282, MET283, ILE327 and 4 more
  • 6ZGT · Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem… · FIV A501 · binds LEU28, CYS57, PHE60, TYR119, LEU145, ARG280, PHE335, PHE359 and 2 more

Residues it binds most

PHE 4, LEU 4, CYS 3, ARG 4, TYR 4, ILE 2, THR 2, GLN 2, GLU 2, GLY 2 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • MN · Manganese (II) ion
  • BYN · hydroxylated prenyl-FMN
  • FMN · Flavin mononucleotide
  • PEG · Di(hydroxyethyl)ether

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