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UniProt Q2FZP6

Udp-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Q2FZP6)

Udp-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (UniProt Q2FZP6), EC 6.3.2.7: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against…

UniProt
Q2FZP6
Protein
Udp-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase
EC
6.3.2.7
Experimental structures
2
Predicted models
1
Ligands
3
Pockets
7 · 2 records with a druggable one

Structures

3 records of Q2FZP6 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4C12X-ray Crystal Structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys and ADPx-ray diffractionAUML, ADP, MG4 (best 0.81)
4C12X-ray crystal structure of staphylococcus aureus mure with udp-murnac-ala-glu-lys and ADPx-ray diffractionA——
Q2FZP6AlphaFold monomer V2.0 prediction for udp-N-acetylmuramoyl-L-alanyl- D-glutamate--L-lysine ligase…predictedA—3 (best 0.77)

Ligands

  • ADP · Adenosine-5'-diphosphate · in 1 record
  • MG · Magnesium ion · in 1 record
  • UML · Uridine 5'Diphospho N-acetyl muramoyl-L-Alanyl-D-Glutamyl-L-Lysine · in 1 record

Experiment against prediction

Elsewhere

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