UniProt Q2A5E5
DNA-directed RNA polymerase subunit alpha 1 (Q2A5E5)
DNA-directed RNA polymerase subunit alpha 1 (UniProt Q2A5E5), EC 2.7.7.6: 6 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2A5E5
- Protein
- DNA-directed RNA polymerase subunit alpha 1
- EC
- 2.7.7.6
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 12 · 3 records with a druggable one
Structures
7 records of Q2A5E5 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WMP | F. tularensis RNAPs70-iglA DNA complex | electron microscopy | A | — | 4 (best 0.84) |
| 6WMP | F. tularensis RNAPS70-igla DNA complex | electron microscopy | A | — | — |
| 6WMR | F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex | electron microscopy | A | — | 2 (best 0.84) |
| 6WMR | F. tularensis RNAPS70-(mgla-sspa)-igla DNA complex | electron microscopy | A | — | — |
| 6WMT | F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex | electron microscopy | A | — | 3 (best 0.84) |
| 6WMT | F. tularensis RNAPS70-(mgla-sspa)-ppgpp-pigr-igla DNA complex | electron microscopy | A | — | — |
| Q2A5E5 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha 1 (Q2A5E5) | predicted | A | — | 3 (best 0.36) |
Experiment against prediction
- 6WMP chain A against the predicted model Q2A5E5: TM-score 0.94, RMSD 1.68 Å
- 6WMP chain A against the predicted model Q2A5E5: TM-score 0.94, RMSD 1.68 Å
- 6WMR chain A against the predicted model Q2A5E5: TM-score 0.93, RMSD 1.80 Å
- 6WMR chain A against the predicted model Q2A5E5: TM-score 0.93, RMSD 1.80 Å
- 6WMT chain A against the predicted model Q2A5E5: TM-score 0.93, RMSD 1.81 Å
- 6WMT chain A against the predicted model Q2A5E5: TM-score 0.93, RMSD 1.81 Å
Elsewhere
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