UniProt Q2A4H7
DNA-directed RNA polymerase subunit alpha 2 (Q2A4H7)
DNA-directed RNA polymerase subunit alpha 2 (UniProt Q2A4H7), EC 2.7.7.6: 6 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2A4H7
- Protein
- DNA-directed RNA polymerase subunit alpha 2
- EC
- 2.7.7.6
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 14 · 3 records with a druggable one
Structures
7 records of Q2A4H7 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WMP | F. tularensis RNAPs70-iglA DNA complex | electron microscopy | B | — | 4 (best 0.84) |
| 6WMP | F. tularensis RNAPS70-igla DNA complex | electron microscopy | B | — | — |
| 6WMR | F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex | electron microscopy | B | — | 3 (best 0.84) |
| 6WMR | F. tularensis RNAPS70-(mgla-sspa)-igla DNA complex | electron microscopy | B | — | — |
| 6WMT | F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex | electron microscopy | B | — | 4 (best 0.84) |
| 6WMT | F. tularensis RNAPS70-(mgla-sspa)-ppgpp-pigr-igla DNA complex | electron microscopy | B | — | — |
| Q2A4H7 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha 2 (Q2A4H7) | predicted | A | — | 3 (best 0.48) |
Experiment against prediction
- 6WMP chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
- 6WMP chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
- 6WMT chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
- 6WMT chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
- 6WMR chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
- 6WMR chain B against the predicted model Q2A4H7: TM-score 0.90, RMSD 2.09 Å
Elsewhere
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