UniProt Q2A1P5
Topoisomerase IV, subunit B (Q2A1P5)
Topoisomerase IV, subunit B (UniProt Q2A1P5), EC 5.99.1.3: 8 experimental structures on GenesisL1, 5 ligands bound, 38 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q2A1P5
- Protein
- Topoisomerase IV, subunit B
- EC
- 5.99.1.3
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 38 · 8 records with a druggable one
Structures
8 records of Q2A1P5 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HXZ | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided… | x-ray diffraction | A, B | 19Y | 5 (best 0.63) |
| 4HXZ | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided… | x-ray diffraction | A, B | 19Y | 5 (best 0.63) |
| 4HY1 | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided… | x-ray diffraction | A, B | 19X | 5 (best 0.66) |
| 4HY1 | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided… | x-ray diffraction | A, B | 19X | 5 (best 0.66) |
| 4HYM | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided… | x-ray diffraction | A, B | CJC | 5 (best 0.67) |
| 4HYM | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided… | x-ray diffraction | A, B | CJC | 5 (best 0.67) |
| 4KQV | Topoisomerase iv atp binding domain of francisella tularensis in complex with a small molecule… | x-ray diffraction | A, B | IOD, DOO | 4 (best 0.63) |
| 4KQV | Topoisomerase IV ATP binding domain of francisella tularensis in complex with a small molecule… | x-ray diffraction | A, B | IOD, DOO | 4 (best 0.63) |
Ligands
- 19X · 6-({4-[(3R)-3-aminopyrrolidin-1-yl]-5-chloro-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)-1H-isoindol-1-one · in 2 records
- 19Y · 6-ethyl-4-methoxy-2-(pyridin-3-ylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde · in 2 records
- CJC · 7-({4-[(3R)-3-aminopyrrolidin-1-yl]-5-chloro-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)pyrido[2,3-b]pyrazin-2(1H)-one · in 2 records
- DOO · 6-fluoro-4-[(3aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl]-N-methyl-2-[(2-methylpyrimidin-5-yl)oxy]-9H-pyrimido[4,5-b]indol-8-amine · in 2 records
- IOD · Iodide ion · in 2 records
Elsewhere
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