UniProt Q29599
2'-5'-oligoadenylate synthase 1 (Q29599)
2'-5'-oligoadenylate synthase 1 (UniProt Q29599): 10 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q29599
- Protein
- 2'-5'-oligoadenylate synthase 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of Q29599 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PX5 | Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral… | x-ray diffraction | A, B | — | — |
| 1PX5 | Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral… | x-ray diffraction | A, B | — | — |
| 4RWN | Crystal structure of the pre-reactive state of porcine OAS1 | x-ray diffraction | A | — | — |
| 4RWN | Crystal structure of the pre-reactive state of porcine OAS1 | x-ray diffraction | A | — | — |
| 4RWO | Crystal structure of the porcine OAS1 L149R mutant in complex with dsRNA and ApCpp in the AMP donor… | x-ray diffraction | A | — | — |
| 4RWO | Crystal structure of the porcine OAS1 L149R mutant in complex with dsrna and apcpp in the AMP donor… | x-ray diffraction | A | — | — |
| 4RWP | Crystal structure of porcine OAS1 in complex with dsRNA | x-ray diffraction | A | — | — |
| 4RWP | Crystal structure of porcine OAS1 in complex with dsrna | x-ray diffraction | A | — | — |
| 4RWQ | Crystal structure of the apo-state of porcine OAS1 | x-ray diffraction | A, B | — | — |
| 4RWQ | Crystal structure of the apo-state of porcine OAS1 | x-ray diffraction | A, B | — | — |
| Q29599 | AlphaFold monomer V2.0 prediction for 2'-5'-oligoadenylate synthase 1 (Q29599) | predicted | A | — | 3 (best 0.58) |
Experiment against prediction
- 1PX5 chain A against the predicted model Q29599: TM-score 0.99, RMSD 0.74 Å
- 1PX5 chain A against the predicted model Q29599: TM-score 0.99, RMSD 0.74 Å
- 1PX5 chain B against the predicted model Q29599: TM-score 0.98, RMSD 1.08 Å
- 1PX5 chain B against the predicted model Q29599: TM-score 0.98, RMSD 1.08 Å
- 4RWQ chain A against the predicted model Q29599: TM-score 0.97, RMSD 1.15 Å
- 4RWQ chain A against the predicted model Q29599: TM-score 0.97, RMSD 1.15 Å
- 4RWP chain A against the predicted model Q29599: TM-score 0.91, RMSD 2.43 Å
- 4RWP chain A against the predicted model Q29599: TM-score 0.91, RMSD 2.43 Å
- 4RWO chain A against the predicted model Q29599: TM-score 0.91, RMSD 2.40 Å
- 4RWO chain A against the predicted model Q29599: TM-score 0.91, RMSD 2.40 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.