UniProt Q26710
Alternative oxidase, mitochondrial (Q26710)
Alternative oxidase, mitochondrial (UniProt Q26710), EC 1.-.-.-: 15 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q26710
- Protein
- Alternative oxidase, mitochondrial
- EC
- 1.-.-.-
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 36 · 2 records with a druggable one
Structures
16 records of Q26710 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VV9 | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei | x-ray diffraction | A, B, C, D | — | — |
| 3VV9 | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei | x-ray diffraction | A, B, C, D | — | — |
| 3VVA | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofura… | x-ray diffraction | A, B, C, D | — | — |
| 3VVA | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei with… | x-ray diffraction | A, B, C, D | — | — |
| 3W54 | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with… | x-ray diffraction | A, B, C, D | — | — |
| 3W54 | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei with… | x-ray diffraction | A, B, C, D | — | — |
| 5GN7 | Crystal structure of alternative oxidase from trypanosoma brucei brucei complexed with cumarin… | x-ray diffraction | A, B, C, D | — | — |
| 5GN9 | Crystal structure of alternative oxidase from Trypanosoma brucei brucei complexed with cumarin… | x-ray diffraction | A, B, C, D | FE, 6Y0 | 19 (best 0.77) |
| 5GN9 | Crystal structure of alternative oxidase from trypanosoma brucei brucei complexed with cumarin… | x-ray diffraction | A, B, C, D | — | — |
| 5ZDP | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ferulenol | x-ray diffraction | A, B, C, D | FE, OH, OXY, 9AU | — |
| 5ZDP | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei with ferulenol | x-ray diffraction | A, B, C, D | FE, OH, OXY, 9AU | — |
| 5ZDQ | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with… | x-ray diffraction | A, B, C, D | FE, OH, RNB, SO4 | — |
| 5ZDQ | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei with… | x-ray diffraction | A, B, C, D | FE, OH, RNB, SO4 | — |
| 5ZDR | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofura… | x-ray diffraction | A, B, C, D | FE, OH, CHW | 17 (best 0.79) |
| 5ZDR | Crystal structure of cyanide-insensitive alternative oxidase from trypanosoma brucei with… | x-ray diffraction | A, B, C, D | FE, OH, CHW | — |
| Q26710 | AlphaFold monomer V2.0 prediction for alternative oxidase, mitochondrial (Q26710) | predicted | A | — | — |
Ligands
- FE · Fe (III) ion · in 7 records
- OH · Hydroxide ion · in 6 records
- 9AU · 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6, 10-trienyl]chromen-2-one · in 2 records
- CHW · 3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde · in 2 records
- OXY · Oxygen molecule · in 2 records
- RNB · 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde · in 2 records
- SO4 · Sulfate ion · in 2 records
- 6Y0 · 4-butyl-7,8-bis(oxidanyl)chromen-2-one · in 1 record
Experiment against prediction
- 5GN9 chain C against the predicted model Q26710: TM-score 0.98, RMSD 0.87 Å
- 5GN9 chain C against the predicted model Q26710: TM-score 0.98, RMSD 0.87 Å
- 5ZDP chain D against the predicted model Q26710: TM-score 0.98, RMSD 0.90 Å
- 5ZDP chain D against the predicted model Q26710: TM-score 0.98, RMSD 0.90 Å
- 5GN9 chain D against the predicted model Q26710: TM-score 0.98, RMSD 0.89 Å
- 5GN9 chain D against the predicted model Q26710: TM-score 0.98, RMSD 0.89 Å
- 5ZDP chain C against the predicted model Q26710: TM-score 0.98, RMSD 0.92 Å
- 5ZDP chain C against the predicted model Q26710: TM-score 0.98, RMSD 0.92 Å
- 5GN7 chain D against the predicted model Q26710: TM-score 0.98, RMSD 0.90 Å
- 3W54 chain A against the predicted model Q26710: TM-score 0.98, RMSD 0.93 Å
Elsewhere
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