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UniProt Q24324

Dual specificity mitogen-activated protein kinase kinase dSOR1 (Q24324)

Dual specificity mitogen-activated protein kinase kinase dSOR1 (UniProt Q24324), EC 2.7.12.2: 1 experimental structure and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment…

UniProt
Q24324
Protein
Dual specificity mitogen-activated protein kinase kinase dSOR1
EC
2.7.12.2
Experimental structures
1
Predicted models
1
Ligands
3
Pockets
8 · 1 record with a druggable one

Structures

2 records of Q24324 in the MolNFT archive: 1 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8BW9Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYPelectron microscopyCANP, QOM, MG8 (best 0.84)
Q24324AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase…predictedA——

Ligands

  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record
  • MG · Magnesium ion · in 1 record
  • QOM · Trametinib · in 1 record

Experiment against prediction

Elsewhere

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