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UniProt Q1R2J4

Type 1 fimbiral adhesin FimH (Q1R2J4)

Type 1 fimbiral adhesin FimH (UniProt Q1R2J4): 6 experimental structures on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q1R2J4
Protein
Type 1 fimbiral adhesin FimH
Experimental structures
6
Predicted models
0
Ligands
4
Pockets
7 · 2 records with a druggable one

Structures

6 records of Q1R2J4 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5JQICrystal structure of FimH A62S from E. coli UTI89 bound to FimG N-terminal extensionx-ray diffractionH, B, D, F—6 (best 0.73)
5JQICrystal structure of fimh A62S from E. COLI UTI89 bound to fimg N- terminal extensionx-ray diffractionH, B, D, F——
5JR4Crystal structure of FimH A27V/V163A from E. coli UTI89 bound to FimG N-terminal extensionx-ray diffractionACA—
5JR4Crystal structure of fimh A27V/V163A from E. COLI UTI89 bound to fimg N-terminal extensionx-ray diffractionA——
7Q3NCryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH…electron microscopyFNAG, BMA, MAN1 (best 0.64)
7Q3NCryo-EM of the complex between human uromodulin (UMOD)/TAMM-horsfall protein (thp) and the fimh…electron microscopyFNAG, BMA, MAN—

Ligands

  • BMA · beta-D-mannopyranose · in 2 records
  • MAN · alpha-D-mannopyranose · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • CA · Calcium ion · in 1 record

Elsewhere

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