UniProt Q1HG43
Isoform 2 of Dual oxidase maturation factor 1 (Q1HG43)
Isoform 2 of Dual oxidase maturation factor 1 (UniProt Q1HG43): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q1HG43
- Protein
- Isoform 2 of Dual oxidase maturation factor 1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 2 records with a druggable one
Structures
5 records of Q1HG43 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7D3E | Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state | electron microscopy | B, D | NAG, BMA, MAN | 12 (best 0.87) |
| 7D3E | Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state | electron microscopy | B, D | NAG, MAN | — |
| 7D3F | Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state | electron microscopy | B, D | NAG, BMA, MAN | 14 (best 0.87) |
| 7D3F | Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state | electron microscopy | B, D | NAG, BMA, MAN | — |
| Q1HG43 | AlphaFold monomer V2.0 prediction for dual oxidase maturation factor 1 (Q1HG43) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7D3F chain B against the predicted model Q1HG43: TM-score 1.00, RMSD 0.37 Å
- 7D3F chain B against the predicted model Q1HG43: TM-score 1.00, RMSD 0.37 Å
- 7D3F chain D against the predicted model Q1HG43: TM-score 1.00, RMSD 0.37 Å
- 7D3F chain D against the predicted model Q1HG43: TM-score 1.00, RMSD 0.37 Å
- 7D3E chain B against the predicted model Q1HG43: TM-score 1.00, RMSD 0.38 Å
- 7D3E chain B against the predicted model Q1HG43: TM-score 1.00, RMSD 0.38 Å
- 7D3E chain D against the predicted model Q1HG43: TM-score 1.00, RMSD 0.38 Å
- 7D3E chain D against the predicted model Q1HG43: TM-score 1.00, RMSD 0.38 Å
Elsewhere
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