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UniProt Q1HG43

Isoform 2 of Dual oxidase maturation factor 1 (Q1HG43)

Isoform 2 of Dual oxidase maturation factor 1 (UniProt Q1HG43): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
Q1HG43
Protein
Isoform 2 of Dual oxidase maturation factor 1
Experimental structures
4
Predicted models
1
Ligands
3
Pockets
26 · 2 records with a druggable one

Structures

5 records of Q1HG43 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7D3ECryo-EM structure of human DUOX1-DUOXA1 in low-calcium stateelectron microscopyB, DNAG, BMA, MAN12 (best 0.87)
7D3ECryo-EM structure of human DUOX1-DUOXA1 in low-calcium stateelectron microscopyB, DNAG, MAN—
7D3FCryo-EM structure of human DUOX1-DUOXA1 in high-calcium stateelectron microscopyB, DNAG, BMA, MAN14 (best 0.87)
7D3FCryo-EM structure of human DUOX1-DUOXA1 in high-calcium stateelectron microscopyB, DNAG, BMA, MAN—
Q1HG43AlphaFold monomer V2.0 prediction for dual oxidase maturation factor 1 (Q1HG43)predictedA——

Ligands

  • MAN · alpha-D-mannopyranose · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • BMA · beta-D-mannopyranose · in 3 records

Experiment against prediction

Elsewhere

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