UniProt Q1GBI9
Energy-coupling factor transporter ATP-binding protein EcfA2 (Q1GBI9)
Energy-coupling factor transporter ATP-binding protein EcfA2 (UniProt Q1GBI9), EC 3.6.3.-: 15 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 44 pockets. Binding sites, druggability and experiment…
- UniProt
- Q1GBI9
- Protein
- Energy-coupling factor transporter ATP-binding protein EcfA2
- EC
- 3.6.3.-
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 44 · 8 records with a druggable one
Structures
16 records of Q1GBI9 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5D3M | Folate ecf transporter: amppnp bound state | x-ray diffraction | B, F | — | — |
| 5JSZ | Folate ECF transporter: apo state | x-ray diffraction | B, F | — | 5 (best 0.84) |
| 5JSZ | Folate ecf transporter: apo state | x-ray diffraction | B, F | — | 5 (best 0.84) |
| 6FNP | Crystal structure of ECF-CbrT, a cobalamin transporter | x-ray diffraction | C, G | — | 4 (best 0.85) |
| 6FNP | Crystal structure of ecf-cbrt, a cobalamin transporter | x-ray diffraction | C, G | — | — |
| 6ZG3 | the structure of ECF PanT transporter in a complex with a nanobody | x-ray diffraction | B, G | — | 10 (best 0.82) |
| 6ZG3 | The structure of ecf pant transporter in a complex with a nanobody | x-ray diffraction | B, G | — | — |
| 7NNT | Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles | electron microscopy | B | — | — |
| 7NNT | Cryo-EM structure of the folate-specific ecf transporter complex in ddm micelles | electron microscopy | B | — | — |
| 7NNU | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs | electron microscopy | B | — | 3 (best 0.82) |
| 7NNU | Cryo-EM structure of the folate-specific ecf transporter complex in MSP2N2 lipid nanodiscs | electron microscopy | B | — | — |
| 8BMP | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to… | electron microscopy | B | ADP, MG | — |
| 8BMQ | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to… | electron microscopy | B | ANP, MG | 4 (best 0.81) |
| 8BMR | Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open… | electron microscopy | B | — | 8 (best 0.78) |
| 8BMS | Cryo-EM structure of the mutant solitary ECF module 2EQ in MSP2N2 lipid nanodiscs in the ATPase… | electron microscopy | B | ATP, MG | 5 (best 0.81) |
| Q1GBI9 | AlphaFold monomer V2.0 prediction for energy-coupling factor transporter ATP-binding protein ECFA2… | predicted | A | — | — |
Ligands
Experiment against prediction
- 7NNT chain B against the predicted model Q1GBI9: TM-score 0.99, RMSD 0.73 Å
- 7NNT chain B against the predicted model Q1GBI9: TM-score 0.99, RMSD 0.73 Å
- 8BMP chain B against the predicted model Q1GBI9: TM-score 0.99, RMSD 0.76 Å
- 8BMR chain B against the predicted model Q1GBI9: TM-score 0.98, RMSD 0.82 Å
- 8BMQ chain B against the predicted model Q1GBI9: TM-score 0.98, RMSD 0.80 Å
- 7NNU chain B against the predicted model Q1GBI9: TM-score 0.98, RMSD 0.92 Å
- 7NNU chain B against the predicted model Q1GBI9: TM-score 0.98, RMSD 0.92 Å
- 5D3M chain F against the predicted model Q1GBI9: TM-score 0.98, RMSD 0.99 Å
- 5D3M chain B against the predicted model Q1GBI9: TM-score 0.98, RMSD 1.01 Å
- 6ZG3 chain B against the predicted model Q1GBI9: TM-score 0.97, RMSD 1.19 Å
Elsewhere
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