UniProt Q16816
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (Q16816)
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (UniProt Q16816), EC 2.7.11.1, 2.7.11.19: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 25 pockets. Binding sites…
- UniProt
- Q16816
- Protein
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
- EC
- 2.7.11.1, 2.7.11.19, 2.7.11.26
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 25 · 6 records with a druggable one
Structures
6 records of Q16816 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JFK | PhK holoenzyme in inactive state, muscle isoform | electron microscopy | C, G, K, O | FAR | 7 (best 0.85) |
| 8JFL | PhK holoenzyme in active state, muscle isoform | electron microscopy | C, G, O, K | FAR | 2 (best 0.76) |
| 8XY7 | hPhK alpha-gamma subcomplex in active state | electron microscopy | C | FAR | 2 (best 0.75) |
| 8XYA | hPhK alpha-beta-gamma-delta subcomplex in inactive state | electron microscopy | C | FAR | 7 (best 0.83) |
| 8XYB | hPhK gamma-delta subcomplex in inactive state | electron microscopy | C | FAR | 6 (best 0.75) |
| Q16816 | AlphaFold monomer V2.0 prediction for phosphorylase B kinase gamma catalytic chain, skeletal… | predicted | A | — | 1 (best 0.65) |
Ligands
- FAR · Farnesyl · in 5 records
Experiment against prediction
- 8JFK chain C against the predicted model Q16816: TM-score 0.76, RMSD 2.39 Å
- 8XYA chain C against the predicted model Q16816: TM-score 0.76, RMSD 2.39 Å
- 8XYB chain C against the predicted model Q16816: TM-score 0.76, RMSD 2.39 Å
- 8JFL chain C against the predicted model Q16816: TM-score 0.58, RMSD 2.32 Å
- 8XY7 chain C against the predicted model Q16816: TM-score 0.58, RMSD 2.32 Å
Elsewhere
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