UniProt Q16581
C3a anaphylatoxin chemotactic receptor (Q16581)
C3a anaphylatoxin chemotactic receptor (UniProt Q16581): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q16581
- Protein
- C3a anaphylatoxin chemotactic receptor
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 35 · 7 records with a druggable one
Structures
8 records of Q16581 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8HK2 | C3aR-Gi-C3a protein complex | electron microscopy | A | CLR, PLM | 8 (best 0.77) |
| 8I95 | Structure of EP54-C3aR-Go complex | electron microscopy | C | — | 4 (best 0.72) |
| 8I97 | Structure of Apo-C3aR-Go complex (Glacios) | electron microscopy | C | — | 5 (best 0.76) |
| 8I9A | Structure of EP54-C3aR-Gq complex | electron microscopy | C | — | 4 (best 0.75) |
| 8I9L | Structure of C3a-C3aR-Go complex (Composite map) | electron microscopy | C | — | 4 (best 0.72) |
| 8I9S | Structure of Apo-C3aR-Go complex (Titan) | electron microscopy | C | — | 6 (best 0.75) |
| 8JA3 | Structure of beta-arrestin1 in complex with C3aRpp | electron microscopy | U, V | — | 4 (best 0.71) |
| Q16581 | AlphaFold monomer V2.0 prediction for C3A anaphylatoxin chemotactic receptor (Q16581) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8I9L chain C against the predicted model Q16581: TM-score 0.92, RMSD 2.13 Å
- 8I97 chain C against the predicted model Q16581: TM-score 0.92, RMSD 2.18 Å
- 8I9S chain C against the predicted model Q16581: TM-score 0.92, RMSD 2.19 Å
- 8I9A chain C against the predicted model Q16581: TM-score 0.92, RMSD 2.14 Å
- 8I95 chain C against the predicted model Q16581: TM-score 0.92, RMSD 2.22 Å
- 8HK2 chain A against the predicted model Q16581: TM-score 0.91, RMSD 2.24 Å
- 8JA3 chain V against the predicted model Q16581: TM-score 0.50, RMSD 1.18 Å
- 8JA3 chain U against the predicted model Q16581: TM-score 0.46, RMSD 1.34 Å
Elsewhere
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