UniProt Q16394
Exostosin-1 (Q16394)
Exostosin-1 (UniProt Q16394), EC 2.4.1.224, 2.4.1.225: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q16394
- Protein
- Exostosin-1
- EC
- 2.4.1.224, 2.4.1.225
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 2 records with a druggable one
Structures
3 records of Q16394 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SCK | Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with a 7-sugar… | electron microscopy | A | NDG, UDP, NAG | 14 (best 0.88) |
| 7UQY | Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with UDP-GlcA | electron microscopy | A | UDP | 12 (best 0.89) |
| Q16394 | AlphaFold monomer V2.0 prediction for exostosin-1 (Q16394) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UQY chain A against the predicted model Q16394: TM-score 0.98, RMSD 1.40 Å
- 7SCK chain A against the predicted model Q16394: TM-score 0.98, RMSD 1.46 Å
Elsewhere
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