UniProt Q15738
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (Q15738)
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (UniProt Q15738), EC 1.1.1.170: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment…
- UniProt
- Q15738
- Protein
- Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
- EC
- 1.1.1.170
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
4 records of Q15738 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JKG | The NAD+-free form of human nsdhl | x-ray diffraction | A, B | — | — |
| 6JKH | The NAD+-bound form of human NSDHL | x-ray diffraction | A, B | NAD | 9 (best 0.56) |
| 6JKH | The NAD+-bound form of human nsdhl | x-ray diffraction | A, B | NAD | — |
| Q15738 | AlphaFold monomer V2.0 prediction for sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating… | predicted | A | — | 1 (best 0.81) |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 2 records
Experiment against prediction
- 6JKH chain B against the predicted model Q15738: TM-score 0.85, RMSD 1.92 Å
- 6JKH chain B against the predicted model Q15738: TM-score 0.85, RMSD 1.92 Å
- 6JKH chain A against the predicted model Q15738: TM-score 0.84, RMSD 1.99 Å
- 6JKH chain A against the predicted model Q15738: TM-score 0.84, RMSD 1.99 Å
- 6JKG chain A against the predicted model Q15738: TM-score 0.84, RMSD 2.03 Å
- 6JKG chain B against the predicted model Q15738: TM-score 0.84, RMSD 2.02 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.