UniProt Q15582
Transforming growth factor-beta-induced protein ig-h3 (Q15582)
Transforming growth factor-beta-induced protein ig-h3 (UniProt Q15582): 18 experimental structures and 1 predicted model on GenesisL1, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15582
- Protein
- Transforming growth factor-beta-induced protein ig-h3
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 54 · 5 records with a druggable one
Structures
19 records of Q15582 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X3B | Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3 | solution nmr | A | — | — |
| 1X3B | Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein ig-H3 | solution nmr | A | — | — |
| 2LTB | Wild-type FAS1-4 | solution nmr | A | — | — |
| 2LTB | Wild-type FAS1-4 | solution nmr | A | — | — |
| 2LTC | Fas1-4, R555W | solution nmr | A | — | — |
| 2LTC | FAS1-4, R555W | solution nmr | A | — | — |
| 2VXP | The fourth FAS1 domain structure of human Bigh3 | x-ray diffraction | A, B | — | — |
| 2VXP | The fourth FAS1 domain structure of human BIGH3 | x-ray diffraction | A, B | — | — |
| 5NV6 | Structure of human transforming growth factor beta-induced protein (TGFBIp). | x-ray diffraction | A, B | — | 16 (best 0.67) |
| 5NV6 | Structure of human transforming growth factor beta-induced protein (tgfbip). | x-ray diffraction | A, B | — | — |
| 7AS7 | Crystal structure of the GCD-associated TGFBIp mutant R124H | x-ray diffraction | A | — | 4 (best 0.62) |
| 7AS7 | Crystal structure of the gcd-associated tgfbip mutant R124H | x-ray diffraction | A | — | — |
| 7ASC | TGFBIp mutant A546T | x-ray diffraction | A, B | — | 20 (best 0.68) |
| 7ASC | Tgfbip mutant A546T | x-ray diffraction | A, B | — | — |
| 7ASG | TGFBIp mutant R555W | x-ray diffraction | A | — | 6 (best 0.63) |
| 7ASG | Tgfbip mutant R555W | x-ray diffraction | A | — | — |
| 8HGA | Monomer structure of transforming growth factor beta induced protein (TGFBIp) G623R fibril | solid-state nmr | A, B, C, D | — | — |
| 8HIA | Structure of transforming growth factor beta induced protein (TGFBIp) G623R fibril | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | 8 (best 0.80) |
| Q15582 | AlphaFold monomer V2.0 prediction for transforming growth factor- beta-induced protein ig-H3… | predicted | A | — | — |
Experiment against prediction
- 2VXP chain B against the predicted model Q15582: TM-score 0.97, RMSD 0.73 Å
- 2VXP chain B against the predicted model Q15582: TM-score 0.97, RMSD 0.73 Å
- 2VXP chain A against the predicted model Q15582: TM-score 0.97, RMSD 0.79 Å
- 2VXP chain A against the predicted model Q15582: TM-score 0.97, RMSD 0.79 Å
- 5NV6 chain B against the predicted model Q15582: TM-score 0.97, RMSD 1.77 Å
- 5NV6 chain B against the predicted model Q15582: TM-score 0.97, RMSD 1.77 Å
- 7ASC chain A against the predicted model Q15582: TM-score 0.97, RMSD 1.74 Å
- 7ASC chain A against the predicted model Q15582: TM-score 0.97, RMSD 1.74 Å
- 7ASC chain B against the predicted model Q15582: TM-score 0.97, RMSD 1.79 Å
- 7ASC chain B against the predicted model Q15582: TM-score 0.97, RMSD 1.79 Å
Elsewhere
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