UniProt Q15303
Q15303
Q15303 (UniProt Q15303): 20 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15303
- Experimental structures
- 20
- Predicted models
- 1
Structures
21 records of Q15303 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AHX | Crystal structure of ErbB4/HER4 extracellular domain | x-ray diffraction | A, B | — | — |
| 2AHX | Crystal structure of ERBB4/HER4 extracellular domain | x-ray diffraction | A, B | — | — |
| 2L2T | Solution NMR structure of the ErbB4 dimeric membrane domain | solution nmr | A, B | — | — |
| 2L2T | Solution NMR structure of the ERBB4 dimeric membrane domain | solution nmr | A, B | — | — |
| 2LCX | Spatial Structure of the ErbB4 dimeric TM domain | solution nmr | A, B | — | — |
| 2LCX | Spatial structure of the ERBB4 dimeric tm domain | solution nmr | A, B | — | — |
| 2R4B | ErbB4 kinase domain complexed with a thienopyrimidine inhibitor | x-ray diffraction | A, B | — | — |
| 2R4B | ERBB4 kinase domain complexed with a thienopyrimidine inhibitor | x-ray diffraction | A, B | — | — |
| 3BBT | crystal structure of the ErbB4 kinase in complex with lapatinib | x-ray diffraction | B, D | — | — |
| 3BBT | Crystal structure of the ERBB4 kinase in complex with lapatinib | x-ray diffraction | B, D | — | — |
| 3BBW | crystal structure of the ErbB4 kinase in its inactive conformation | x-ray diffraction | B, A | — | — |
| 3BBW | Crystal structure of the ERBB4 kinase in its inactive conformation | x-ray diffraction | B, A | — | — |
| 3BCE | Crystal structure of the ErbB4 kinase | x-ray diffraction | A, B, C | — | — |
| 3BCE | Crystal structure of the ERBB4 kinase | x-ray diffraction | A, B, C | — | — |
| 3U2P | Crystal structure of N-terminal three extracellular domains of ErbB4/Her4 | x-ray diffraction | A | — | — |
| 3U2P | Crystal structure of N-terminal three extracellular domains of ERBB4/HER4 | x-ray diffraction | A | — | — |
| 3U7U | Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3U7U | Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3U9U | Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of… | x-ray diffraction | E, F | — | — |
| 3U9U | Crystal structure of extracellular domain of human ERBB4/HER4 in complex with the Fab fragment of… | x-ray diffraction | E, F | — | — |
| Q15303 | AlphaFold monomer V2.0 prediction for receptor tyrosine-protein kinase erbb-4 (Q15303) | predicted | A | — | — |
Experiment against prediction
- 3BCE chain C against the predicted model Q15303: TM-score 0.97, RMSD 1.18 Å
- 3BCE chain C against the predicted model Q15303: TM-score 0.97, RMSD 1.18 Å
- 3BCE chain A against the predicted model Q15303: TM-score 0.97, RMSD 1.18 Å
- 3BCE chain A against the predicted model Q15303: TM-score 0.97, RMSD 1.18 Å
- 3BCE chain B against the predicted model Q15303: TM-score 0.97, RMSD 1.33 Å
- 3BCE chain B against the predicted model Q15303: TM-score 0.97, RMSD 1.33 Å
- 2AHX chain A against the predicted model Q15303: TM-score 0.97, RMSD 1.65 Å
- 2AHX chain A against the predicted model Q15303: TM-score 0.97, RMSD 1.65 Å
- 3U9U chain F against the predicted model Q15303: TM-score 0.96, RMSD 1.66 Å
- 3U9U chain F against the predicted model Q15303: TM-score 0.96, RMSD 1.66 Å
Elsewhere
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