UniProt Q15025
TNFAIP3-interacting protein 1 (Q15025)
TNFAIP3-interacting protein 1 (UniProt Q15025): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15025
- Protein
- TNFAIP3-interacting protein 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
11 records of Q15025 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EAL | The structure of the A20-Binding Inhibitor of NF-kB 1 in complex with di-ubiquitin | x-ray diffraction | B, C, E, F | — | 3 (best 0.60) |
| 7EAL | The structure of the A20-binding inhibitor of nf-kb 1 in complex with di-ubiquitin | x-ray diffraction | B, C, E, F | — | — |
| 7EAO | The structure of the A20-binding inhibitor of NF-kB 1 in complex with tri-ubiquitin | x-ray diffraction | B, C | — | 2 (best 0.45) |
| 7EAO | The structure of the A20-binding inhibitor of nf-kb 1 in complex with tri-ubiquitin | x-ray diffraction | B, C | — | — |
| 7EB9 | The structure of the A20-binding inhibitor of NF-kB 1 in complex with tetra-ubiquitin | x-ray diffraction | B, C | — | 1 (best 0.34) |
| 7EB9 | The structure of the A20-binding inhibitor of nf-kb 1 in complex with tetra-ubiquitin | x-ray diffraction | B, C | — | — |
| 8YFK | Crystal structure of FIP200 claw/TNIP1_FIR_pS123 | x-ray diffraction | B, H, D, F | MG | 1 (best 0.50) |
| 8YFM | Crystal structure of FIP200 claw/TNIP1_FIR_pS122 | x-ray diffraction | B, E | — | 2 (best 0.34) |
| 8YFN | Crystal structure of FIP200 claw in complex with TNIP1_FIR_pS123 peptide with an elongated C… | x-ray diffraction | B, D | — | — |
| 9D34 | FIP200 C-terminal CLAW domain (resid. 1490-1594) in complex with phosphorylated TNIP1 FIP200… | x-ray diffraction | C | — | — |
| Q15025 | AlphaFold monomer V2.0 prediction for TNFAIP3-interacting protein 1 (Q15025) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 7EB9 chain C against the predicted model Q15025: TM-score 0.91, RMSD 0.84 Å
- 7EB9 chain C against the predicted model Q15025: TM-score 0.91, RMSD 0.84 Å
- 7EAL chain B against the predicted model Q15025: TM-score 0.91, RMSD 1.24 Å
- 7EAL chain B against the predicted model Q15025: TM-score 0.91, RMSD 1.24 Å
- 7EB9 chain B against the predicted model Q15025: TM-score 0.91, RMSD 0.91 Å
- 7EB9 chain B against the predicted model Q15025: TM-score 0.91, RMSD 0.91 Å
- 7EAL chain F against the predicted model Q15025: TM-score 0.89, RMSD 1.08 Å
- 7EAL chain F against the predicted model Q15025: TM-score 0.89, RMSD 1.08 Å
- 7EAO chain B against the predicted model Q15025: TM-score 0.88, RMSD 1.25 Å
- 7EAO chain B against the predicted model Q15025: TM-score 0.88, RMSD 1.25 Å
Elsewhere
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