UniProt Q14831
Metabotropic glutamate receptor 7 (Q14831)
Metabotropic glutamate receptor 7 (UniProt Q14831): 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14831
- Protein
- Metabotropic glutamate receptor 7
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 4 · 1 record with a druggable one
Structures
6 records of Q14831 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3MQ4 | Metabotropic glutamate receptor mGluR7 complexed with LY341495 antagonist | x-ray diffraction | A | — | — |
| 3MQ4 | Metabotropic glutamate receptor MGLUR7 complexed with LY341495 antagonist | x-ray diffraction | A | — | — |
| 5C5C | Human metabotropic glutamate receptor 7, extracellular ligand binding domain | x-ray diffraction | A | NAG, CA, UNX | 4 (best 0.67) |
| 5C5C | Human metabotropic glutamate receptor 7, extracellular ligand binding domain | x-ray diffraction | A | — | — |
| 7EPC | Cryo-EM structure of inactive MGLU7 homodimer | electron microscopy | — | — | |
| Q14831 | AlphaFold monomer V2.0 prediction for metabotropic glutamate receptor 7 (Q14831) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5C5C chain A against the predicted model Q14831: TM-score 0.94, RMSD 2.11 Å
- 5C5C chain A against the predicted model Q14831: TM-score 0.94, RMSD 2.11 Å
- 3MQ4 chain A against the predicted model Q14831: TM-score 0.87, RMSD 3.06 Å
- 3MQ4 chain A against the predicted model Q14831: TM-score 0.87, RMSD 3.06 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.