UniProt Q14703
Membrane-bound transcription factor site-1 protease (Q14703)
Membrane-bound transcription factor site-1 protease (UniProt Q14703), EC 3.4.21.112: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q14703
- Protein
- Membrane-bound transcription factor site-1 protease
- EC
- 3.4.21.112
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 1 record with a druggable one
Structures
3 records of Q14703 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UW8 | Site-one protease and SPRING | electron microscopy | A | NAG, CA | 7 (best 0.77) |
| 8UWC | Site-one protease without SPRING | electron microscopy | A | NAG | 6 (best 0.46) |
| Q14703 | AlphaFold monomer V2.0 prediction for membrane-bound transcription factor site-1 protease (Q14703) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8UWC chain A against the predicted model Q14703: TM-score 0.98, RMSD 1.11 Å
- 8UW8 chain A against the predicted model Q14703: TM-score 0.97, RMSD 1.53 Å
Elsewhere
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