UniProt Q14534
Q14534
Q14534 (UniProt Q14534): 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14534
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
Structures
4 records of Q14534 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C6N | Human squalene epoxidase (sqle, squalene monooxygenase) structure with FAD and cmpd-4" | x-ray diffraction | A, B | SO4, CPS, EKV, FAD | — |
| 6C6P | Human squalene epoxidase (sqle, squalene monooxygenase) structure with FAD and nb-598 | x-ray diffraction | A, B | CPS, EMV, FAD | — |
| 6C6R | Human squalene epoxidase (sqle, squalene monooxygenase) structure with FAD | x-ray diffraction | A, B | FAD, CPS | — |
| Q14534 | AlphaFold monomer V2.0 prediction for squalene monooxygenase (Q14534) | predicted | A | — | — |
Ligands
- CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · in 3 records
- FAD · Flavin-adenine dinucleotide · in 3 records
- EKV · N-[(3-{[dimethyl(2-methylphenyl)silyl]methoxy}phenyl) methyl]-N-ethyl-6-methoxy-6-methylhepta-2,4-diyn-1-amine · in 1 record
- EMV · (2E)-N-({3-[([3,3'-bithiophen]-5-yl) methoxy]phenyl}methyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine · in 1 record
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 6C6N chain A against the predicted model Q14534: TM-score 1.00, RMSD 0.28 Å
- 6C6P chain A against the predicted model Q14534: TM-score 1.00, RMSD 0.30 Å
- 6C6P chain B against the predicted model Q14534: TM-score 1.00, RMSD 0.32 Å
- 6C6R chain A against the predicted model Q14534: TM-score 1.00, RMSD 0.33 Å
- 6C6N chain B against the predicted model Q14534: TM-score 1.00, RMSD 0.35 Å
- 6C6R chain B against the predicted model Q14534: TM-score 1.00, RMSD 0.38 Å
Elsewhere
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