UniProt Q14397
Q14397
Q14397 (UniProt Q14397): 36 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14397
- Experimental structures
- 36
- Predicted models
- 1
Structures
37 records of Q14397 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BB9 | Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate | x-ray diffraction | A | — | — |
| 4BB9 | Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate | x-ray diffraction | A | — | — |
| 4BBA | Crystal structure of glucokinase regulatory protein complexed to phosphate | x-ray diffraction | A | — | — |
| 4BBA | Crystal structure of glucokinase regulatory protein complexed to phosphate | x-ray diffraction | A | — | — |
| 4LY9 | Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]me… | x-ray diffraction | A, B | — | — |
| 4LY9 | Human gkrp complexed to amg-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2… | x-ray diffraction | A, B | — | — |
| 4MQU | Human GKRP complexed to AMG-3969 and S6P | x-ray diffraction | A, B | — | — |
| 4MQU | Human gkrp complexed to amg-3969 and S6P | x-ray diffraction | A, B | — | — |
| 4MRO | Human GKRP bound to AMG-5980 and S6P | x-ray diffraction | A, B | — | — |
| 4MRO | Human gkrp bound to amg-5980 and S6P | x-ray diffraction | A, B | — | — |
| 4MSU | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4MSU | Human gkrp bound to amg-6861 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OHK | Human GKRP bound to AMG-2526 and S6P | x-ray diffraction | A, B | — | — |
| 4OHK | Human gkrp bound to amg-2526 and S6P | x-ray diffraction | A, B | — | — |
| 4OHM | Human GKRP bound to AMG-0771 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OHM | Human gkrp bound to amg-0771 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OHO | Human GKRP bound to AMG-2668 | x-ray diffraction | A, B | — | — |
| 4OHO | Human gkrp bound to amg-2668 | x-ray diffraction | A, B | — | — |
| 4OHP | Human GKRP bound to AMG-3227 and S6P | x-ray diffraction | A, B | — | — |
| 4OHP | Human gkrp bound to amg-3227 and S6P | x-ray diffraction | A, B | — | — |
| 4OLH | Human GKRP Bound to AMG5106 and Sorbitol-6-Phosphate | x-ray diffraction | A, B | — | — |
| 4OLH | Human gkrp bound to AMG5106 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OP1 | GKRP bound to AMG0556 and Sorbitol-6-Phosphate | x-ray diffraction | A, B | — | — |
| 4OP1 | Gkrp bound to AMG0556 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OP2 | GKRP bound to AMG-0471 and Sorbitol-6-Phosphate | x-ray diffraction | A, B | — | — |
| 4OP2 | Gkrp bound to amg-0471 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OP3 | Human GKRP bound to AMG-5112 and Sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4OP3 | Human gkrp bound to amg-5112 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PX2 | Human GKRP bound to AMG2882 and Sorbitol-6-Phosphate | x-ray diffraction | A, B | — | — |
| 4PX2 | Human gkrp bound to AMG2882 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PX3 | Human GKRP bound to AMG-3295 and Sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PX3 | Human gkrp bound to amg-3295 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PX5 | Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PX5 | Human gkrp bound to amg-0696 and sorbitol-6-phosphate | x-ray diffraction | A, B | — | — |
| 4PXS | Human GKRP bound to AMG-0265 (N-[(R)-(2-CHLOROPHENYL){7-[4-(2-HYDROXYPROPAN-2-YL)… | x-ray diffraction | A, B | — | — |
| 4PXS | Human gkrp bound to amg-0265 (N-[(R)-(2-CHLOROPHENYL){7-[4-(2- hydroxypropan-2-yl)… | x-ray diffraction | A, B | — | — |
| Q14397 | AlphaFold monomer V2.0 prediction for glucokinase regulatory protein (Q14397) | predicted | A | — | — |
Experiment against prediction
- 4BB9 chain A against the predicted model Q14397: TM-score 0.97, RMSD 0.95 Å
- 4BB9 chain A against the predicted model Q14397: TM-score 0.97, RMSD 0.95 Å
- 4BBA chain A against the predicted model Q14397: TM-score 0.97, RMSD 0.96 Å
- 4BBA chain A against the predicted model Q14397: TM-score 0.97, RMSD 0.96 Å
- 4PX5 chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.93 Å
- 4PX5 chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.93 Å
- 4PXS chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.94 Å
- 4PXS chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.94 Å
- 4PX2 chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.96 Å
- 4PX2 chain A against the predicted model Q14397: TM-score 0.93, RMSD 1.96 Å
Elsewhere
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