UniProt Q14203
Dynactin-1 (Q14203)
Dynactin-1 (UniProt Q14203): 18 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14203
- Protein
- Dynactin-1
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
19 records of Q14203 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TXQ | Crystal structure of the EB1 C-terminal domain complexed with the CAP-Gly domain of p150Glued | x-ray diffraction | A | — | — |
| 1TXQ | Crystal structure of the EB1 C-terminal domain complexed with the cap-gly domain of P150GLUED | x-ray diffraction | A | — | — |
| 2COY | Solution structure of the CAP-Gly domain in human Dynactin 1 | solution nmr | A | — | — |
| 2COY | Solution structure of the cap-gly domain in human dynactin 1 | solution nmr | A | — | — |
| 2HKN | Crystal structure of the CAP-Gly domain of human Dynactin-1 (p150-Glued) | x-ray diffraction | A, B | — | — |
| 2HKN | Crystal structure of the cap-gly domain of human dynactin-1 (P150- glued) | x-ray diffraction | A, B | — | — |
| 2HKQ | Crystal structure of the C-terminal domain of human EB1 in complex with the CAP-Gly domain of human… | x-ray diffraction | B | — | — |
| 2HKQ | Crystal structure of the C-terminal domain of human EB1 in complex with the cap-gly domain of human… | x-ray diffraction | B | — | — |
| 2HL3 | Crystal structure of the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued) in complex… | x-ray diffraction | A, B | — | 1 (best 0.44) |
| 2HL3 | Crystal structure of the A49M mutant cap-gly domain of human dynactin- 1 (P150-glued) in complex… | x-ray diffraction | A, B | — | — |
| 2HL5 | Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly… | x-ray diffraction | C, D | — | — |
| 2HL5 | Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant cap-gly… | x-ray diffraction | C, D | — | — |
| 2HQH | Crystal structure of p150Glued and CLIP-170 | x-ray diffraction | A, B, C, D | — | — |
| 2HQH | Crystal structure of P150GLUED and clip-170 | x-ray diffraction | A, B, C, D | — | — |
| 3E2U | Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of… | x-ray diffraction | A, B, C, D | — | — |
| 3E2U | Crystal structure of the zink-knuckle 2 domain of human clip-170 in complex with cap-gly domain of… | x-ray diffraction | A, B, C, D | — | — |
| 3TQ7 | EB1c/EB3c heterodimer in complex with the CAP-Gly domain of P150glued | x-ray diffraction | P, Q | — | — |
| 3TQ7 | EB1C/EB3C heterodimer in complex with the cap-gly domain of P150GLUED | x-ray diffraction | P, Q | — | — |
| Q14203 | AlphaFold monomer V2.0 prediction for dynactin subunit 1 (Q14203) | predicted | A | — | — |
Experiment against prediction
- 3TQ7 chain Q against the predicted model Q14203: TM-score 0.97, RMSD 0.50 Å
- 3TQ7 chain Q against the predicted model Q14203: TM-score 0.97, RMSD 0.50 Å
- 3TQ7 chain P against the predicted model Q14203: TM-score 0.97, RMSD 0.50 Å
- 3TQ7 chain P against the predicted model Q14203: TM-score 0.97, RMSD 0.50 Å
- 2HQH chain C against the predicted model Q14203: TM-score 0.97, RMSD 0.53 Å
- 2HQH chain C against the predicted model Q14203: TM-score 0.97, RMSD 0.53 Å
- 3E2U chain A against the predicted model Q14203: TM-score 0.97, RMSD 0.57 Å
- 3E2U chain A against the predicted model Q14203: TM-score 0.97, RMSD 0.57 Å
- 2HKQ chain B against the predicted model Q14203: TM-score 0.97, RMSD 0.66 Å
- 2HKQ chain B against the predicted model Q14203: TM-score 0.97, RMSD 0.66 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.