UniProt Q14118
10-mer Peptide from Dystroglycan (Q14118)
10-mer Peptide from Dystroglycan (UniProt Q14118): 11 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14118
- Protein
- 10-mer Peptide from Dystroglycan
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 3 · 1 record with a druggable one
Structures
12 records of Q14118 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EG4 | Structure of a dystrophin ww domain fragment in complex with a beta-dystroglycan peptide | x-ray diffraction | P | — | — |
| 1EG4 | Structure of a dystrophin ww domain fragment in complex with a beta-dystroglycan peptide | x-ray diffraction | P | — | — |
| 2MK7 | Tetra-O-GalNAc glycosylated mucin sequence from alpha dystroglycan mucin domain | solution nmr | A | — | — |
| 2MK7 | Tetra-O-galnac glycosylated mucin sequence from alpha dystroglycan mucin domain | solution nmr | A | — | — |
| 5GGP | Crystal structure of N-terminal domain of human protein O-mannose… | x-ray diffraction | C, D | MAN, NAG | — |
| 5GGP | Crystal structure of N-terminal domain of human protein O-mannose… | x-ray diffraction | C, D | — | — |
| 5LLK | Crystal structure of human alpha-dystroglycan | x-ray diffraction | A | — | — |
| 5LLK | Crystal structure of human alpha-dystroglycan | x-ray diffraction | A | — | — |
| 6JJY | Crystal Structure of KIBRA and beta-Dystroglycan | x-ray diffraction | U | SO4 | — |
| 6JJY | Crystal structure of kibra and beta-dystroglycan | x-ray diffraction | U | SO4 | — |
| 8UF4 | Crystal structure of wildtype dystroglycan proteolytic domain (juxtamembrane domain) | x-ray diffraction | A, B, C, D | CA, CL | 3 (best 0.85) |
| Q14118 | AlphaFold monomer V2.0 prediction for dystroglycan (Q14118) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5LLK chain A against the predicted model Q14118: TM-score 0.99, RMSD 0.53 Å
- 5LLK chain A against the predicted model Q14118: TM-score 0.99, RMSD 0.53 Å
- 8UF4 chain D against the predicted model Q14118: TM-score 0.96, RMSD 0.62 Å
- 8UF4 chain B against the predicted model Q14118: TM-score 0.95, RMSD 1.19 Å
- 8UF4 chain C against the predicted model Q14118: TM-score 0.94, RMSD 1.26 Å
- 8UF4 chain A against the predicted model Q14118: TM-score 0.94, RMSD 1.61 Å
- 5GGP chain C against the predicted model Q14118: TM-score 0.78, RMSD 0.39 Å
- 5GGP chain C against the predicted model Q14118: TM-score 0.78, RMSD 0.39 Å
- 2MK7 chain A against the predicted model Q14118: TM-score 0.47, RMSD 1.06 Å
- 2MK7 chain A against the predicted model Q14118: TM-score 0.47, RMSD 1.06 Å
Elsewhere
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