UniProt Q14108
Lysosome membrane protein 2 (Q14108)
Lysosome membrane protein 2 (UniProt Q14108): 18 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14108
- Protein
- Lysosome membrane protein 2
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 30 · 4 records with a druggable one
Structures
19 records of Q14108 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4F7B | Structure of the lysosomal domain of limp-2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4F7B | Structure of the lysosomal domain of limp-2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4Q4B | Crystal structure of LIMP-2 (space group C2221) | x-ray diffraction | A | — | — |
| 4Q4B | Crystal structure of limp-2 (space group C2221) | x-ray diffraction | A | — | — |
| 4Q4F | Crystal structure of LIMP-2 (space group C2) | x-ray diffraction | A | — | — |
| 4Q4F | Crystal structure of limp-2 (space group C2) | x-ray diffraction | A | — | — |
| 4TVZ | Crystal Structure of SCARB2 in Neural Condition (pH7.5) | x-ray diffraction | A, B | NAG, BMA, MAN | 8 (best 0.85) |
| 4TVZ | Crystal structure of SCARB2 in neural condition (PH7.5) | x-ray diffraction | A, B | — | — |
| 4TW0 | Crystal Structure of SCARB2 in Acidic Condition (pH4.8) | x-ray diffraction | A, B, C, D | — | — |
| 4TW0 | Crystal structure of SCARB2 in acidic condition (PH4.8) | x-ray diffraction | A, B, C, D | — | — |
| 4TW2 | Crystal Structure of SCARB2 in Neural Condition (pH7.5) | x-ray diffraction | A, B | — | — |
| 4TW2 | Crystal structure of SCARB2 in neural condition (PH7.5) | x-ray diffraction | A, B | — | — |
| 5UPH | Lipids bound lysosomal integral membrane protein 2 | x-ray diffraction | A, B | NAG, BMA, MAN, M6D, CLR, PCW | 5 (best 0.86) |
| 5UPH | Lipids bound lysosomal integral membrane protein 2 | x-ray diffraction | A, B | NAG, MAN, M6D, BMA, CLR, PCW | — |
| 5XBM | Structure of SCARB2-JL2 complex | x-ray diffraction | C, F | NAG, BMA, MAN | 11 (best 0.84) |
| 5XBM | Structure of SCARB2-JL2 complex | x-ray diffraction | C, F | NAG, BMA, MAN | — |
| 6I2K | Structure of EV71 complexed with its receptor SCARB2 | electron microscopy | E | NAG, BMA, MAN | — |
| 6I2K | Structure of EV71 complexed with its receptor SCARB2 | electron microscopy | E | NAG, BMA, MAN | — |
| Q14108 | AlphaFold monomer V2.0 prediction for lysosome membrane protein 2 (Q14108) | predicted | A | — | 6 (best 0.86) |
Ligands
Experiment against prediction
- 4Q4B chain A against the predicted model Q14108: TM-score 1.00, RMSD 0.41 Å
- 4Q4B chain A against the predicted model Q14108: TM-score 1.00, RMSD 0.41 Å
- 4Q4F chain A against the predicted model Q14108: TM-score 1.00, RMSD 0.47 Å
- 4Q4F chain A against the predicted model Q14108: TM-score 1.00, RMSD 0.47 Å
- 4TW2 chain A against the predicted model Q14108: TM-score 0.99, RMSD 0.61 Å
- 4TW2 chain A against the predicted model Q14108: TM-score 0.99, RMSD 0.61 Å
- 5XBM chain F against the predicted model Q14108: TM-score 0.99, RMSD 0.66 Å
- 5XBM chain F against the predicted model Q14108: TM-score 0.99, RMSD 0.66 Å
- 6I2K chain E against the predicted model Q14108: TM-score 0.99, RMSD 0.70 Å
- 6I2K chain E against the predicted model Q14108: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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