UniProt Q14028
Cyclic nucleotide-gated cation channel beta-1 (Q14028)
Cyclic nucleotide-gated cation channel beta-1 (UniProt Q14028): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q14028
- Protein
- Cyclic nucleotide-gated cation channel beta-1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 2 records with a druggable one
Structures
13 records of Q14028 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7RH9 | Cryo-EM structure of human rod CNGA1/B1 channel in apo state | electron microscopy | B | — | 10 (best 0.74) |
| 7RH9 | Cryo-EM structure of human rod CNGA1/B1 channel in apo state | electron microscopy | B | — | — |
| 7RHG | Cryo-EM structure of human rod CNGA1/B1 channel in cAMP-bound state | electron microscopy | B | CMP | — |
| 7RHG | Cryo-EM structure of human rod CNGA1/B1 channel in camp-bound state | electron microscopy | B | CMP | — |
| 7RHH | Cryo-EM structure of human rod CNGA1/B1 channel in cgmp-bound openi state | electron microscopy | B | PCG | — |
| 7RHI | Cryo-EM structure of human rod CNGA1/B1 channel in cgmp-bound openii state | electron microscopy | B | PCG | — |
| 7RHJ | Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state | electron microscopy | B | PCG, 5H0 | — |
| 7RHJ | Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-diltiazem- blocked open state | electron microscopy | B | PCG, 5H0 | — |
| 7RHK | Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-trapped closed state | electron microscopy | B | PCG, 5H0 | 10 (best 0.83) |
| 7RHK | Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-diltiazem- trapped closed state | electron microscopy | B | PCG, 5H0 | — |
| 7RHL | Cryo-EM structure of human rod apo CNGA1/B1 channel with clz coiled coil | electron microscopy | B | — | — |
| 8DGK | NMR structure of calmodulin bound to N-terminal site in the beta-subunit of cyclic nucleotide-gated… | solution nmr | B | — | — |
| Q14028 | AlphaFold monomer V2.0 prediction for cyclic nucleotide-gated cation channel beta-1 (Q14028) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7RHI chain B against the predicted model Q14028: TM-score 0.94, RMSD 2.08 Å
- 7RH9 chain B against the predicted model Q14028: TM-score 0.92, RMSD 2.44 Å
- 7RH9 chain B against the predicted model Q14028: TM-score 0.92, RMSD 2.44 Å
- 7RHG chain B against the predicted model Q14028: TM-score 0.91, RMSD 2.53 Å
- 7RHG chain B against the predicted model Q14028: TM-score 0.91, RMSD 2.53 Å
- 7RHJ chain B against the predicted model Q14028: TM-score 0.91, RMSD 2.57 Å
- 7RHJ chain B against the predicted model Q14028: TM-score 0.91, RMSD 2.57 Å
- 7RHK chain B against the predicted model Q14028: TM-score 0.90, RMSD 2.70 Å
- 7RHK chain B against the predicted model Q14028: TM-score 0.90, RMSD 2.70 Å
- 7RHH chain B against the predicted model Q14028: TM-score 0.89, RMSD 2.97 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.