Ligand · 5H0
5H0 · (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
5H0, (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate (C22 H26 N2 O4 S, 414.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding…
- Component
- 5H0
- Formula
- C22 H26 N2 O4 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
5H0 in 4 structures; the first of them:
- 7RHJ · Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state · 5H0 D801 · binds LEU360, THR361, THR362, GLY385, PHE389, ALA390, VAL393, THR845 and 15 more
- 7RHK · Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-trapped closed state · 5H0 A1102 · binds THR361, ILE363, VAL386, PHE389, LEU843, ILE844, PHE872, ILE876 and 17 more
- 7RHJ · Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-diltiazem- blocked open state · 5H0 D801 · binds LEU360, THR361, THR362, GLY385, PHE389, ALA390, VAL393, THR845 and 15 more
- 7RHK · Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-diltiazem- trapped closed state · 5H0 A1102 · binds ILE363, PHE389, LEU843, ILE844, PHE872, ILE876, LEU360, THR361 and 13 more
Residues it binds most
THR 4, PHE 4, VAL 4, ILE 4, LEU 4, GLY 4, ALA 3 (residue and the binding sites it lines).
Found with
- PCG · Cyclic guanosine monophosphate
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