UniProt Q13873
Bone morphogenetic protein receptor type-2 (Q13873)
Bone morphogenetic protein receptor type-2 (UniProt Q13873), EC 2.7.11.30: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q13873
- Protein
- Bone morphogenetic protein receptor type-2
- EC
- 2.7.11.30
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 5 records with a druggable one
Structures
13 records of Q13873 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3G2F | Crystal structure of the kinase domain of bone morphogenetic protein receptor type II (BMPR2) at… | x-ray diffraction | A, B | — | — |
| 3G2F | Crystal structure of the kinase domain of bone morphogenetic protein receptor type II (BMPR2) at… | x-ray diffraction | A, B | — | — |
| 6UNP | Crystal structure of the kinase domain of BMPR2-D485G | x-ray diffraction | A, B | ADP, MG, SO4 | 7 (best 0.85) |
| 6UNP | Crystal structure of the kinase domain of BMPR2-D485G | x-ray diffraction | A, B | ADP, MG, SO4 | — |
| 7PPA | High resolution structure of bone morphogenetic protein receptor type II (BMPRII) extracellular… | x-ray diffraction | C, D | — | 3 (best 0.55) |
| 7PPA | High resolution structure of bone morphogenetic protein receptor type II (bmprii) extracellular… | x-ray diffraction | C, D | — | — |
| 7PPB | 2.4 angstrom crystal structure of bone morphogenetic protein receptor type II (BMPRII)… | x-ray diffraction | B | — | 1 (best 0.56) |
| 7PPB | 2.4 ångström crystal structure of bone morphogenetic protein receptor type II (bmprii)… | x-ray diffraction | B | — | — |
| 7PPC | Ternary signalling complex of BMP10 bound to ALK1 and BMPRII | x-ray diffraction | I, J, K, L | — | 3 (best 0.62) |
| 7PPC | Ternary signalling complex of BMP10 bound to ALK1 and bmprii | x-ray diffraction | I, J, K, L | — | — |
| 7U5O | Crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in… | x-ray diffraction | E, F, G | — | 6 (best 0.64) |
| 7U5O | Crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in… | x-ray diffraction | E, F, G | — | — |
| Q13873 | AlphaFold monomer V2.0 prediction for bone morphogenetic protein receptor type-2 (Q13873) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6UNP chain B against the predicted model Q13873: TM-score 0.98, RMSD 1.18 Å
- 6UNP chain B against the predicted model Q13873: TM-score 0.98, RMSD 1.18 Å
- 6UNP chain A against the predicted model Q13873: TM-score 0.98, RMSD 1.17 Å
- 6UNP chain A against the predicted model Q13873: TM-score 0.98, RMSD 1.17 Å
- 3G2F chain A against the predicted model Q13873: TM-score 0.98, RMSD 1.23 Å
- 3G2F chain A against the predicted model Q13873: TM-score 0.98, RMSD 1.23 Å
- 3G2F chain B against the predicted model Q13873: TM-score 0.98, RMSD 1.20 Å
- 3G2F chain B against the predicted model Q13873: TM-score 0.98, RMSD 1.20 Å
- 7PPC chain I against the predicted model Q13873: TM-score 0.87, RMSD 1.46 Å
- 7PPC chain I against the predicted model Q13873: TM-score 0.87, RMSD 1.46 Å
Elsewhere
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