UniProt Q13867
Bleomycin hydrolase (Q13867)
Bleomycin hydrolase (UniProt Q13867), EC 3.4.22.40: 9 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13867
- Protein
- Bleomycin hydrolase
- EC
- 3.4.22.40
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
10 records of Q13867 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CB5 | Human bleomycin hydrolase. | x-ray diffraction | A, B, C | — | — |
| 1CB5 | Human bleomycin hydrolase. | x-ray diffraction | A, B, C | — | — |
| 2CB5 | Human bleomycin hydrolase, C73S/DELE455 mutant | x-ray diffraction | A, B | — | — |
| 2CB5 | Human bleomycin hydrolase, C73S/DELE455 mutant | x-ray diffraction | A, B | — | — |
| 7V5L | Crystal structure of human bleomycin hydrolase | x-ray diffraction | A, B, C, D | — | — |
| 7V5S | Crystal structure of human bleomycin hydrolase C73A mutant | x-ray diffraction | A | — | — |
| 7V5T | Crystal structure of human bleomycin hydrolase C73S mutant | x-ray diffraction | A | — | — |
| 7XF9 | Crystal structure of human bleomycin hydrolase H372A mutant | x-ray diffraction | A | — | 3 (best 0.55) |
| 7XF9 | Crystal structure of human bleomycin hydrolase H372A mutant | x-ray diffraction | A | — | — |
| Q13867 | AlphaFold monomer V2.0 prediction for bleomycin hydrolase (Q13867) | predicted | A | — | — |
Experiment against prediction
- 1CB5 chain B against the predicted model Q13867: TM-score 1.00, RMSD 0.33 Å
- 1CB5 chain C against the predicted model Q13867: TM-score 1.00, RMSD 0.33 Å
- 1CB5 chain A against the predicted model Q13867: TM-score 1.00, RMSD 0.33 Å
- 1CB5 chain A against the predicted model Q13867: TM-score 1.00, RMSD 0.33 Å
- 2CB5 chain A against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
- 2CB5 chain A against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
- 7V5L chain A against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
- 7V5L chain B against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
- 7V5L chain C against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
- 7V5L chain D against the predicted model Q13867: TM-score 1.00, RMSD 0.37 Å
Elsewhere
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