UniProt Q13586
Stromal interaction molecule 1 (Q13586)
Stromal interaction molecule 1 (UniProt Q13586): 12 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13586
- Protein
- Stromal interaction molecule 1
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
13 records of Q13586 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2K60 | NMR structure of calcium-loaded STIM1 EF-SAM | solution nmr | A | — | — |
| 2K60 | NMR structure of calcium-loaded STIM1 ef-SAM | solution nmr | A | — | — |
| 2MAJ | Solution Structure of the STIM1 CC1-CC2 homodimer. | solution nmr | A, C | — | — |
| 2MAJ | Solution structure of the STIM1 CC1-CC2 homodimer. | solution nmr | A, C | — | — |
| 2MAK | Solution structure of the STIM1 CC1-CC2 homodimer in complex with two Orai1 C-terminal domains. | solution nmr | A, C | — | — |
| 2MAK | Solution structure of the STIM1 CC1-CC2 homodimer in complex with two ORAI1 C-terminal domains. | solution nmr | A, C | — | — |
| 3TEQ | Crystal structure of SOAR domain | x-ray diffraction | A, B, C, D | — | — |
| 3TEQ | Crystal structure of soar domain | x-ray diffraction | A, B, C, D | — | — |
| 4O9B | The Structure of CC1-IH in human STIM1. | x-ray diffraction | A, B, C, D | — | — |
| 4O9B | The structure of CC1-ih in human STIM1. | x-ray diffraction | A, B, C, D | — | — |
| 6YEL | Stromal interaction molecule 1 coiled-coil 1 fragment | solution nmr | A | — | 1 (best 0.35) |
| 6YEL | Stromal interaction molecule 1 coiled-coil 1 fragment | solution nmr | A | — | — |
| Q13586 | AlphaFold monomer V2.0 prediction for stromal interaction molecule 1 (Q13586) | predicted | A | — | 1 (best 0.29) |
Experiment against prediction
- 3TEQ chain B against the predicted model Q13586: TM-score 0.78, RMSD 2.75 Å
- 3TEQ chain B against the predicted model Q13586: TM-score 0.78, RMSD 2.75 Å
- 2K60 chain A against the predicted model Q13586: TM-score 0.78, RMSD 2.71 Å
- 2K60 chain A against the predicted model Q13586: TM-score 0.78, RMSD 2.71 Å
- 3TEQ chain A against the predicted model Q13586: TM-score 0.77, RMSD 2.68 Å
- 3TEQ chain A against the predicted model Q13586: TM-score 0.77, RMSD 2.68 Å
- 4O9B chain B against the predicted model Q13586: TM-score 0.70, RMSD 2.50 Å
- 4O9B chain B against the predicted model Q13586: TM-score 0.70, RMSD 2.50 Å
- 4O9B chain C against the predicted model Q13586: TM-score 0.68, RMSD 2.82 Å
- 4O9B chain C against the predicted model Q13586: TM-score 0.68, RMSD 2.82 Å
Elsewhere
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