UniProt Q13501
Sequestosome-1 (Q13501)
Sequestosome-1 (UniProt Q13501): 37 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13501
- Protein
- Sequestosome-1
- Experimental structures
- 37
- Predicted models
- 1
- Ligands
- 1
Structures
38 records of Q13501 in the MolNFT archive: 37 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Q02 | NMR structure of the UBA domain of p62 (SQSTM1) | solution nmr | A | — | — |
| 1Q02 | NMR structure of the uba domain of P62 (SQSTM1) | solution nmr | A | — | — |
| 2JY7 | NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1). RDC refined | solution nmr | A | — | — |
| 2JY7 | NMR structure of the ubiquitin associated (uba) domain of P62 (SQSTM1). rdc refined | solution nmr | A | — | — |
| 2JY8 | NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1) in complex with ubiquitin.… | solution nmr | A | — | — |
| 2JY8 | NMR structure of the ubiquitin associated (uba) domain of P62 (SQSTM1) in complex with ubiquitin.… | solution nmr | A | — | — |
| 2K0B | NMR structure of the UBA domain of p62 (SQSTM1) | solution nmr | X | — | — |
| 2K0B | NMR structure of the uba domain of P62 (SQSTM1) | solution nmr | X | — | — |
| 2KNV | NMR dimer structure of the UBA domain of p62 (SQSTM1) | solution nmr | A, B | — | — |
| 2KNV | NMR dimer structure of the uba domain of P62 (SQSTM1) | solution nmr | A, B | — | — |
| 4MJS | crystal structure of a PB1 complex | x-ray diffraction | B, D, F, H, J, L, N, P, R, T, V, X | — | — |
| 4MJS | Crystal structure of a PB1 complex | x-ray diffraction | B, D, F, H, J, L, N, P, R, T, V, X | — | — |
| 4UF8 | Electron cryo-microscopy structure of PB1-p62 filaments | electron microscopy | A, B, C, I | — | — |
| 4UF8 | Electron cryo-microscopy structure of PB1-P62 filaments | electron microscopy | A, B, C, I | — | — |
| 4UF9 | Electron cryo-microscopy structure of PB1-p62 type T filaments | electron microscopy | A, B, D | — | — |
| 4UF9 | Electron cryo-microscopy structure of PB1-P62 type T filaments | electron microscopy | A, B, D | — | — |
| 5YP7 | p62/SQSTM1 ZZ domain | x-ray diffraction | A, D | ZN | — |
| 5YP7 | P62/SQSTM1 zz domain | x-ray diffraction | A, D | ZN | — |
| 5YP8 | P62/SQSTM1 zz domain with arg-peptide | x-ray diffraction | A, B | ZN | — |
| 5YPA | P62/SQSTM1 zz domain with lys-peptide | x-ray diffraction | A, B | ZN | — |
| 5YPB | P62/SQSTM1 zz domain with his-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 5YPC | P62/SQSTM1 zz domain with phe-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 5YPE | P62/SQSTM1 zz domain with tyr-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 5YPF | p62/SQSTM1 ZZ domain with Trp-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 5YPF | P62/SQSTM1 zz domain with TRP-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 5YPG | p62/SQSTM1 ZZ domain with Leu-peptide | x-ray diffraction | A, B | ZN | — |
| 5YPG | P62/SQSTM1 zz domain with leu-peptide | x-ray diffraction | A, B | ZN | — |
| 5YPH | p62/SQSTM1 ZZ domain with Ile-peptide | x-ray diffraction | A, B | ZN | — |
| 5YPH | P62/SQSTM1 zz domain with ile-peptide | x-ray diffraction | A, B | ZN | — |
| 6JM4 | The crystal structure of PB1 homo-dimer of human P62/SQSTM1 | x-ray diffraction | A, B, D, C | — | — |
| 6KHZ | p62/SQSTM1 ZZ domain with Gly-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 6KHZ | P62/SQSTM1 zz domain with gly-peptide | x-ray diffraction | A, B, C, D | ZN | — |
| 6MIU | Crystal structure of p62 ZZ domain in complex with Arg-Glu peptide | x-ray diffraction | A, B | ZN | — |
| 6MIU | Crystal structure of P62 zz domain in complex with arg-glu peptide | x-ray diffraction | A, B | ZN | — |
| 6MJ7 | Crystal structure of P62 zz domain in complex with free arginine | x-ray diffraction | A | ZN | — |
| 6TGY | Cryo-EM structure of P62-PB1 filament (L-type) | electron microscopy | A | — | — |
| 6TH3 | Cryo-EM structure of P62-PB1 filament (S-type) | electron microscopy | A, B, C | — | — |
| Q13501 | AlphaFold monomer V2.0 prediction for sequestosome-1 (Q13501) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 18 records
Experiment against prediction
- 6JM4 chain D against the predicted model Q13501: TM-score 0.97, RMSD 0.61 Å
- 6JM4 chain A against the predicted model Q13501: TM-score 0.97, RMSD 0.60 Å
- 4MJS chain H against the predicted model Q13501: TM-score 0.97, RMSD 0.64 Å
- 4MJS chain H against the predicted model Q13501: TM-score 0.97, RMSD 0.64 Å
- 4MJS chain L against the predicted model Q13501: TM-score 0.96, RMSD 0.79 Å
- 4MJS chain L against the predicted model Q13501: TM-score 0.96, RMSD 0.79 Å
- 4MJS chain D against the predicted model Q13501: TM-score 0.96, RMSD 0.72 Å
- 4MJS chain D against the predicted model Q13501: TM-score 0.96, RMSD 0.72 Å
- 6JM4 chain C against the predicted model Q13501: TM-score 0.96, RMSD 0.71 Å
- 4MJS chain J against the predicted model Q13501: TM-score 0.96, RMSD 0.79 Å
Elsewhere
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