UniProt Q13489
Baculoviral IAP repeat-containing protein 3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (UniProt Q13489), EC 2.3.2.27: 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q13489
- Protein
- Baculoviral IAP repeat-containing protein 3
- EC
- 2.3.2.27
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 3 records with a druggable one
Structures
13 records of Q13489 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2UVL | Human BIR3 domain of Baculoviral Inhibitor of Apoptosis Repeat- Containing 3 (BIRC3) | x-ray diffraction | A, B | ZN | 1 (best 0.67) |
| 2UVL | Human BIR3 domain of baculoviral inhibitor of apoptosis repeat- containing 3 (BIRC3) | x-ray diffraction | A, B | ZN | 1 (best 0.67) |
| 3EB5 | Structure of the cIAP2 RING domain | x-ray diffraction | A | ZN, NA | — |
| 3EB5 | Structure of the CIAP2 ring domain | x-ray diffraction | A | ZN, NA | — |
| 3EB6 | Structure of the cIAP2 RING domain bound to UbcH5b | x-ray diffraction | A | ZN | 2 (best 0.49) |
| 3EB6 | Structure of the CIAP2 ring domain bound to UBCH5B | x-ray diffraction | A | ZN | 2 (best 0.49) |
| 3M0A | Crystal structure of TRAF2:cIAP2 complex | x-ray diffraction | D | ZN | 1 (best 0.37) |
| 3M0A | Crystal structure of TRAF2:CIAP2 complex | x-ray diffraction | D | ZN | 1 (best 0.37) |
| 3M0D | Crystal structure of the TRAF1:TRAF2:cIAP2 complex | x-ray diffraction | D | ZN | 1 (best 0.45) |
| 3M0D | Crystal structure of the TRAF1:TRAF2:CIAP2 complex | x-ray diffraction | D | ZN | 1 (best 0.45) |
| 7NK0 | Structure of the BIR1 domain of cIAP2 | x-ray diffraction | D, E | ZN | 1 (best 0.29) |
| 7NK0 | Structure of the BIR1 domain of CIAP2 | x-ray diffraction | D, E | ZN | 1 (best 0.29) |
| Q13489 | AlphaFold monomer V2.0 prediction for baculoviral iap repeat- containing protein 3 (Q13489) | predicted | A | — | 6 (best 0.82) |
Ligands
Experiment against prediction
- 7NK0 chain D against the predicted model Q13489: TM-score 0.95, RMSD 0.75 Å
- 7NK0 chain D against the predicted model Q13489: TM-score 0.95, RMSD 0.75 Å
- 2UVL chain A against the predicted model Q13489: TM-score 0.94, RMSD 1.14 Å
- 2UVL chain A against the predicted model Q13489: TM-score 0.94, RMSD 1.14 Å
- 3M0D chain D against the predicted model Q13489: TM-score 0.94, RMSD 1.03 Å
- 3M0D chain D against the predicted model Q13489: TM-score 0.94, RMSD 1.03 Å
- 7NK0 chain E against the predicted model Q13489: TM-score 0.93, RMSD 0.92 Å
- 7NK0 chain E against the predicted model Q13489: TM-score 0.93, RMSD 0.92 Å
- 2UVL chain B against the predicted model Q13489: TM-score 0.92, RMSD 0.86 Å
- 2UVL chain B against the predicted model Q13489: TM-score 0.92, RMSD 0.86 Å
Elsewhere
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