UniProt Q13347
Eukaryotic translation initiation factor 3 subunit I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (UniProt Q13347): 8 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13347
- Protein
- Eukaryotic translation initiation factor 3 subunit I
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
9 records of Q13347 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6YBT | Structure of a human 48S translational initiation complex - eIF3bgi | electron microscopy | 2 | — | 8 (best 0.69) |
| 6YBT | Structure of a human 48S translational initiation complex - EIF3BGI | electron microscopy | 2 | — | — |
| 6ZON | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 | electron microscopy | I | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | I | — | — |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | F | — | — |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | 2 | — | — |
| 8PJ6 | Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3… | electron microscopy | 2 | — | — |
| 8XXN | Cryo-EM structure of the human 43S ribosome with PDCD4 | electron microscopy | 3I | — | — |
| Q13347 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit I (Q13347) | predicted | A | — | — |
Experiment against prediction
- 8OZ0 chain F against the predicted model Q13347: TM-score 0.94, RMSD 1.86 Å
- 8XXN chain 3I against the predicted model Q13347: TM-score 0.91, RMSD 2.37 Å
- 6ZON chain I against the predicted model Q13347: TM-score 0.91, RMSD 2.36 Å
- 7A09 chain I against the predicted model Q13347: TM-score 0.91, RMSD 2.38 Å
- 6YBT chain 2 against the predicted model Q13347: TM-score 0.87, RMSD 2.71 Å
- 6YBT chain 2 against the predicted model Q13347: TM-score 0.87, RMSD 2.71 Å
- 8PJ6 chain 2 against the predicted model Q13347: TM-score 0.85, RMSD 2.95 Å
- 8PJ1 chain 2 against the predicted model Q13347: TM-score 0.84, RMSD 3.01 Å
Elsewhere
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