UniProt Q13324
Corticotropin-releasing factor receptor 2 (Q13324)
Corticotropin-releasing factor receptor 2 (UniProt Q13324): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q13324
- Protein
- Corticotropin-releasing factor receptor 2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 2 records with a druggable one
Structures
4 records of Q13324 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PB1 | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs… | electron microscopy | P | CLR, PLM | 5 (best 0.73) |
| 6PB1 | Cryo-EM structure of urocortin 1-bound corticotropin-releasing factor 2 receptor in complex with gs… | electron microscopy | P | CLR, PLM | — |
| 7TS0 | Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled… | electron microscopy | P | — | 8 (best 0.67) |
| Q13324 | AlphaFold monomer V2.0 prediction for corticotropin-releasing factor receptor 2 (Q13324) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6PB1 chain P against the predicted model Q13324: TM-score 0.95, RMSD 1.66 Å
- 6PB1 chain P against the predicted model Q13324: TM-score 0.95, RMSD 1.66 Å
- 7TS0 chain P against the predicted model Q13324: TM-score 0.91, RMSD 2.23 Å
Elsewhere
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