UniProt Q13283
Ras GTPase-activating protein-binding protein 1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (UniProt Q13283), EC 3.6.4.12, 3.6.4.13: 18 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 40 pockets. Binding sites, druggability and experiment…
- UniProt
- Q13283
- Protein
- Ras GTPase-activating protein-binding protein 1
- EC
- 3.6.4.12, 3.6.4.13
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 40 · 4 records with a druggable one
Structures
19 records of Q13283 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3Q90 | Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 | x-ray diffraction | A, B | — | — |
| 3Q90 | Crystal structure of the NTF2 domain of RAS GTPase-activating protein- binding protein 1 | x-ray diffraction | A, B | — | — |
| 4FCJ | Crystal structure of the NTF2-like domain of human G3BP1 | x-ray diffraction | A, B | — | — |
| 4FCJ | Crystal structure of the NTF2-like domain of human G3BP1 | x-ray diffraction | A, B | — | — |
| 4FCM | Crystal structure of the NTF2-like domain of human G3BP1 in complex with a peptide | x-ray diffraction | A, B | — | — |
| 4FCM | Crystal structure of the NTF2-like domain of human G3BP1 in complex with a peptide | x-ray diffraction | A, B | — | — |
| 4IIA | Low resolution crystal structure of the NTF2-like domain of human G3BP1 | x-ray diffraction | A | — | — |
| 4IIA | Low resolution crystal structure of the NTF2-like domain of human G3BP1 | x-ray diffraction | A | — | — |
| 5FW5 | Crystal structure of human G3BP1 in complex with Semliki Forest Virus nsP3-25 comprising two FGDF… | x-ray diffraction | A, B | SO4, K | — |
| 5FW5 | Crystal structure of human G3BP1 in complex with semliki forest virus NSP3-25 comprising two fgdf… | x-ray diffraction | A, B | — | — |
| 6TA7 | Crystal structure of human G3BP1-NTF2 in complex with human CAPRIN1-derived solomon motif | x-ray diffraction | A, B, D, F, C, E | NA, CL | 9 (best 0.58) |
| 6TA7 | Crystal structure of human G3BP1-NTF2 in complex with human CAPRIN1- derived solomon motif | x-ray diffraction | A, B, D, F, C, E | NA, CL | — |
| 7SUO | Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein | x-ray diffraction | A, B | — | — |
| 7SUO | Crystal structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-cov-2 nucleocapsid protein | x-ray diffraction | A, B | — | — |
| 7XHG | Crystal structure of the NTF2L domain of human G3BP1 in complex with the Caprin-1 derived peptide | x-ray diffraction | A, B, C, D | — | 2 (best 0.67) |
| 8TH5 | Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | 17 (best 0.73) |
| 8TH7 | Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide | x-ray diffraction | A, B | — | 1 (best 0.35) |
| 8V1L | Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule | x-ray diffraction | A, B, C, D, E, F | Y9M | 11 (best 0.73) |
| Q13283 | AlphaFold monomer V2.0 prediction for RAS GTPase-activating protein- binding protein 1 (Q13283) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4FCM chain A against the predicted model Q13283: TM-score 0.99, RMSD 0.39 Å
- 4FCM chain A against the predicted model Q13283: TM-score 0.99, RMSD 0.39 Å
- 7XHG chain B against the predicted model Q13283: TM-score 0.99, RMSD 0.45 Å
- 3Q90 chain A against the predicted model Q13283: TM-score 0.99, RMSD 0.42 Å
- 3Q90 chain A against the predicted model Q13283: TM-score 0.99, RMSD 0.42 Å
- 7XHG chain C against the predicted model Q13283: TM-score 0.99, RMSD 0.49 Å
- 7XHG chain D against the predicted model Q13283: TM-score 0.99, RMSD 0.55 Å
- 8V1L chain B against the predicted model Q13283: TM-score 0.98, RMSD 0.56 Å
- 7SUO chain A against the predicted model Q13283: TM-score 0.98, RMSD 0.59 Å
- 7SUO chain A against the predicted model Q13283: TM-score 0.98, RMSD 0.59 Å
Elsewhere
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