UniProt Q13219
Pappalysin-1 (Q13219)
Pappalysin-1 (UniProt Q13219), EC 3.4.24.79: 7 experimental structures on GenesisL1, 3 ligands bound, 112 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13219
- Protein
- Pappalysin-1
- EC
- 3.4.24.79
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 112 · 6 records with a druggable one
Structures
7 records of Q13219 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UFG | Cryo-EM structure of PAPP-A in complex with IGFBP5 | electron microscopy | A, B | ZN | 20 (best 0.83) |
| 7Y5N | Structure of 1:1 PAPP-A.ProMBP complex(half map) | electron microscopy | C, D | NAG, ZN, CA | 20 (best 0.74) |
| 7Y5Q | Structure of 1:1 PAPP-A.STC2 complex(half map) | electron microscopy | A, B | ZN | 19 (best 0.75) |
| 8A7D | Partial dimer complex of PAPP-A and its inhibitor STC2 | electron microscopy | C, Q | NAG, ZN, CA | 19 (best 0.72) |
| 8A7E | PAPP-A dimer in complex with its inhibitor STC2 | electron microscopy | C, Q | ZN, CA | 14 (best 0.76) |
| 8HGG | Structure of 2:2 PAPP-A.ProMBP complex | electron microscopy | C, D | ZN | 20 (best 0.74) |
| Q13219 | AlphaFold monomer V2.0 prediction for pappalysin-1 (Q13219) | — | — | — |
Ligands
Experiment against prediction
- 7Y5Q chain B against the predicted model P0AEX9: TM-score 0.14, RMSD 7.48 Å
- 7Y5Q chain A against the predicted model P0AEX9: TM-score 0.23, RMSD 6.20 Å
Elsewhere
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