UniProt Q13188
Serine/threonine-protein kinase 3 (Q13188)
Serine/threonine-protein kinase 3 (UniProt Q13188), EC 2.7.11.1: 21 experimental structures on GenesisL1, 6 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13188
- Protein
- Serine/threonine-protein kinase 3
- EC
- 2.7.11.1
- Experimental structures
- 21
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 21 · 3 records with a druggable one
Structures
21 records of Q13188 in the MolNFT archive: 21 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WWS | Crystal structure of Serine/threonine-protein kinase 3 | x-ray diffraction | A, D, C, B | — | — |
| 3WWS | Crystal structure of SERINE/THREONINE-protein kinase 3 | x-ray diffraction | A, D, C, B | — | — |
| 4HKD | Crystal structure of human MST2 SARAH domain | x-ray diffraction | A, B, C, D | — | — |
| 4HKD | Crystal structure of human MST2 sarah domain | x-ray diffraction | A, B, C, D | — | — |
| 4L0N | Crystal structure of STK3 (MST2) SARAH domain | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4L0N | Crystal structure of STK3 (MST2) sarah domain | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4LG4 | Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4LG4 | Structural basis for autoactivation of human MST2 kinase and its regulation by RASSF5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4LGD | Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5 | x-ray diffraction | A, B, C, D | — | — |
| 4LGD | Structural basis for autoactivation of human MST2 kinase and its regulation by RASSF5 | x-ray diffraction | A, B, C, D | — | — |
| 4OH9 | Crystal Structure of the human MST2 SARAH homodimer | x-ray diffraction | A, B | — | — |
| 4OH9 | Crystal structure of the human MST2 sarah homodimer | x-ray diffraction | A, B | — | — |
| 5BRM | Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo… | x-ray diffraction | G, H, I, J, K, L, M, N, O | — | 12 (best 0.72) |
| 5BRM | Structural basis for MOB1-dependent activation of the core mst-lats kinase cascade in hippo… | x-ray diffraction | G, H, I, J, K, L, M, N, O | — | — |
| 5DH3 | Crystal structure of MST2 in complex with XMU-MP-1 | x-ray diffraction | A, B | 5BS, CL, SO4 | — |
| 5DH3 | Crystal structure of MST2 in complex with xmu-mp-1 | x-ray diffraction | A, B | — | — |
| 6AO5 | Crystal structure of human MST2 in complex with SAV1 SARAH domain | x-ray diffraction | A | ANP, MG | 3 (best 0.69) |
| 6AO5 | Crystal structure of human MST2 in complex with SAV1 sarah domain | x-ray diffraction | A | ANP, MG | — |
| 8A66 | Crystal structure of MST2 in complex with XMU-MP-1 | x-ray diffraction | A, B | 5BS, NA | 6 (best 0.67) |
| 8A66 | Crystal structure of MST2 in complex with xmu-mp-1 | x-ray diffraction | A, B | 5BS, NA | — |
| Q13188 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 3 (Q13188) | — | — | — |
Ligands
- 5BS · 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide · in 3 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- MG · Magnesium ion · in 2 records
- NA · Sodium ion · in 2 records
- CL · Chloride ion · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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