UniProt Q13085
Acetyl-CoA carboxylase 1 (Q13085)
Acetyl-CoA carboxylase 1 (UniProt Q13085), EC 6.3.4.14, 6.4.1.2: 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q13085
- Protein
- Acetyl-CoA carboxylase 1
- EC
- 6.3.4.14, 6.4.1.2
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 80 · 4 records with a druggable one
Structures
12 records of Q13085 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YL2 | Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain | x-ray diffraction | A, B | — | — |
| 2YL2 | Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (bc) domain | x-ray diffraction | A, B | — | — |
| 3COJ | Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from… | x-ray diffraction | H, I, J, K, L, M, N, O | — | — |
| 3COJ | Crystal structure of the brct domains of human BRCA1 in complex with a phosphorylated peptide from… | x-ray diffraction | H, I, J, K, L, M, N, O | — | — |
| 4ASI | Crystal structure of human ACACA C-terminal domain | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4ASI | Crystal structure of human acaca C-terminal domain | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6G2D | Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution | electron microscopy | B, C, D, F | — | 20 (best 0.87) |
| 6G2D | Citrate-induced acetyl-CoA carboxylase (acc-cit) filament at 5.4 a resolution | electron microscopy | B, C, D, F | — | — |
| 6G2I | Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution | electron microscopy | D, E, C, F, B, A, G, Q, J, R | — | 20 (best 0.88) |
| 8XL0 | Citrate-induced filament of human acetyl-coenzyme A carboxylase 1 (ACC1-citrate) | electron microscopy | A, B, C, D, E, F | BTN | 20 (best 0.87) |
| 8XL1 | Core region of the human acetyl-CoA carboxylase 1 filament in complex with acetyl-CoA (ACC1-inact) | electron microscopy | A, B | ACO | 20 (best 0.83) |
| Q13085 | AlphaFold monomer V2.0 prediction for acetyl-CoA carboxylase 1 (Q13085) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4ASI chain F against the predicted model Q13085: TM-score 0.99, RMSD 1.06 Å
- 4ASI chain F against the predicted model Q13085: TM-score 0.99, RMSD 1.06 Å
- 4ASI chain B against the predicted model Q13085: TM-score 0.99, RMSD 1.09 Å
- 4ASI chain B against the predicted model Q13085: TM-score 0.99, RMSD 1.09 Å
- 4ASI chain E against the predicted model Q13085: TM-score 0.99, RMSD 1.12 Å
- 4ASI chain E against the predicted model Q13085: TM-score 0.99, RMSD 1.12 Å
- 4ASI chain A against the predicted model Q13085: TM-score 0.98, RMSD 1.44 Å
- 4ASI chain A against the predicted model Q13085: TM-score 0.98, RMSD 1.44 Å
- 8XL1 chain B against the predicted model Q13085: TM-score 0.98, RMSD 1.56 Å
- 4ASI chain C against the predicted model Q13085: TM-score 0.97, RMSD 1.76 Å
Elsewhere
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