UniProt Q12996
Cleavage stimulation factor subunit 3 (Q12996)
Cleavage stimulation factor subunit 3 (UniProt Q12996): 5 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12996
- Protein
- Cleavage stimulation factor subunit 3
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
6 records of Q12996 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6B3X | Crystal structure of CstF-50 in complex with CstF-77 | x-ray diffraction | B | — | — |
| 6B3X | Crystal structure of cstf-50 in complex with cstf-77 | x-ray diffraction | B | — | — |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | electron microscopy | E, F | — | 8 (best 0.82) |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-pas RNA-CSTF77 complex | electron microscopy | E, F | — | — |
| 7ZY4 | Crystal structure of human CstF77 in complex with hFip1 | x-ray diffraction | A, B | — | 4 (best 0.73) |
| Q12996 | AlphaFold monomer V2.0 prediction for cleavage stimulation factor subunit 3 (Q12996) | predicted | A | — | — |
Experiment against prediction
- 6URO chain E against the predicted model Q12996: TM-score 0.99, RMSD 0.99 Å
- 6URO chain E against the predicted model Q12996: TM-score 0.99, RMSD 0.99 Å
- 6URO chain F against the predicted model Q12996: TM-score 0.99, RMSD 0.99 Å
- 6URO chain F against the predicted model Q12996: TM-score 0.99, RMSD 0.99 Å
- 7ZY4 chain B against the predicted model Q12996: TM-score 0.98, RMSD 0.89 Å
- 7ZY4 chain A against the predicted model Q12996: TM-score 0.98, RMSD 0.97 Å
- 6B3X chain B against the predicted model Q12996: TM-score 0.33, RMSD 1.53 Å
- 6B3X chain B against the predicted model Q12996: TM-score 0.33, RMSD 1.53 Å
Elsewhere
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